Overview
This lecture covers the structure and composition of bone tissue, explaining the differences between spongy and compact bone and detailing the organization of osteons.
Bone Composition
- All bones contain connective tissue made of bone cells (osteocytes) and an extracellular matrix.
- The extracellular matrix consists of collagen, ground substance, and calcium phosphate.
Types of Bone Tissue
- Bone tissue includes spongy bone (cancellous bone) and compact bone.
- Spongy bone has a mesh-like network called trabeculae with bone marrow filling the gaps.
- Compact bone makes up the outer layers of bone and provides strength and support.
- The internal layers of bone are made of spongy bone.
Structure of Compact Bone
- Compact bone is organized into structural units called osteons or Haversian systems.
- Osteons run parallel to the long axis of long bones.
- Each osteon contains a central canal (Haversian canal) with blood vessels and nerves.
- Perforating (Volkmann's) canals branch out from central canals at right angles to connect to the periosteum.
- Osteons are surrounded by concentric layers called lamellae.
Bone Cell Organization
- Lacunae are small spaces within lamellae that house osteocytes (bone cells).
- Canaliculi are tiny tunnels that connect lacunae, allowing communication between osteocytes.
Key Terms & Definitions
- Osteocyte â a bone cell embedded in the matrix.
- Extracellular Matrix â the material outside bone cells, including collagen, ground substance, and minerals.
- Spongy (Cancellous) Bone â bone tissue with a mesh-like structure called trabeculae.
- Compact Bone â dense bone forming the outer layer of bones.
- Osteon (Haversian System) â the basic structural unit of compact bone.
- Haversian Canal â central channel in an osteon containing blood vessels and nerves.
- Perforating (Volkmann's) Canal â canals running at right angles, connecting Haversian canals to the periosteum.
- Lamellae â concentric rings of bone matrix around an osteon.
- Lacuna â small cavities in bone that house osteocytes.
- Canaliculi â small channels connecting lacunae for cell communication.
Action Items / Next Steps
- Review the structural differences between compact and spongy bone.
- Study diagrams of osteon and bone tissue organization.