Overview
- Summary of General Biology 2 topics: domains of life, cell types, major kingdoms, physiology, behavior, and ecosystems.
- Emphasis on key definitions, structures, processes, and examples for exam study.
Domains Of Life And Cell Types
- Three domains: Bacteria, Archaea, Eukaryotes.
- Prokaryotes: Bacteria + Archaea; unicellular, binary fission, no nucleus.
- Eukaryotes: multicellular or unicellular, mitosis/meiosis, nucleus and membrane-bound organelles.
- Archaea genetically closer to eukaryotes.
| Feature | Prokaryotes | Eukaryotes |
| Cellularity | Unicellular | Mostly multicellular |
| Division | Binary fission | Mitosis and meiosis |
| Nucleus | Absent | Present |
| Membrane Organelles | Few/none | Many (mitochondria, plastids) |
Bacteria: Classification And Cell Wall
- Classified by metabolism, shape, growth environment, gene sequence, cell wall structure.
- Peptidoglycan is unique to bacteria.
- Gram-positive: single membrane, thick peptidoglycan, stains purple (e.g., Staphylococcus aureus).
- Gram-negative: two membranes with peptidoglycan between, stains pink (e.g., E. coli, cyanobacteria).
- Antibiotics can inhibit peptidoglycan synthesis.
- Lateral (horizontal) gene transfer exchanges genes between prokaryotes.
- Use stable core genes to infer phylogeny.
- Bacterial communities: biofilms — cells secrete sticky polysaccharide matrix (dental plaque, implants, lenses).
Archaea: Membrane Features
- Distinct lipid structure: ether linkages (not ester).
- Membranes often form monolayers rather than bilayers.
Viruses
- Not definitively classified as living; require host to replicate.
- Structure: DNA or RNA core, protein envelope with surface proteins to bind host cells.
- Replicate using host machinery.
Endosymbiotic Theory And Eukaryotic Organelles
- Eukaryotic organelles (mitochondria, plastids) derived from ancestral engulfed bacteria.
- Primary endosymbiosis: direct engulfment of bacteria.
- Secondary endosymbiosis: engulfment of a eukaryote that already contained endosymbionts.
- Engulfment via phagocytosis → formation of vacuole/phagosome from plasma membrane.
Protists
- Eukaryotes that are not plants, animals, or fungi.
- Mostly unicellular; some multicellular.
- Include plankton, phytoplankton, autotrophs, heterotrophs.
- Diatoms: photosynthetic, silicon in cell walls, contribute to fossil fuels.
- Dinoflagellates: photosynthetic, two flagella, can cause toxic red tides.
Fungi
- Synapomorphies: absorptive heterotrophy and chitin in cell walls.
- Forms: multicellular (mushrooms) and unicellular (yeast).
- Structure: mycelium (network) made of hyphae (filaments); mushrooms are spore-producing fruiting bodies.
- Ecological roles: saprotrophic (decomposers), parasitic, pathogenic, mutualistic (mycorrhizae).
- Reproduction: sexual and asexual; life stages include haploid (n), dikaryotic (n+n), diploid (2n).
Animals: Characteristics And Development
- Traits: multicellularity, heterotrophy, internal digestion, movement.
- Origin: choanoflagellate-like ancestor; sponges as simple animals.
- Body symmetry: asymmetry, radial, bilateral.
- Germ layers: diploblasts (2), triploblasts (3).
- Triploblasts subdivide: protostomes (mouth first) and deuterostomes (mouth later).
- Deuterostome groups: echinoderms, hemichordates, chordates.
- Vertebrates: backbone; amniotes (reptiles, birds, mammals) produce amniotic eggs.
- Mammal features: sweat glands, mammary glands, hair, four-chambered heart.
Plants: Types, Adaptations, Life Cycle
- Multicellular autotrophs with cell walls, mitochondria, plastids.
- Groups: algae and green plants; green plants include land plants.
- Land plant categories: non-vascular (mosses) and vascular.
- Vascular plants: seedless and seed plants; seed plants subdivided into gymnosperms (non-flowering) and angiosperms (flowering).
- Key land adaptations: protected embryo, waxy cuticle, stomata, symbiosis with fungi (mycorrhizae).
- Alternation of generations: gametophyte (haploid, photosynthetic) and sporophyte (diploid, nutritionally dependent on gametophyte in some groups).
Flowering Plants: Photoreceptors And Flowering Control
- Photoreceptors contain phytochromes absorbing red (Pr) and far-red (Pfr) light.
- Phytochrome interconverts: Pr ↔ Pfr; prolonged darkness converts Pfr to Pr.
- Long-day plants flower when nights are shorter than threshold (require more daylight).
Photosynthesis: Light Reactions And Carbon Fixation
- Converts sunlight + CO2 → sugars + O2.
- Two stages: light reactions (thylakoid membranes) and carbon fixation (stroma).
- Chlorophyll absorbs light, initiates electron transport chain producing ATP and O2.
- Rubisco enzyme catalyzes CO2 fixation to form carbon intermediates used to make glucose.
Animal Metabolism And Temperature Regulation
- Metabolic rate: energy consumption rate; measured by oxygen consumption.
- Regulators (endotherms): maintain stable internal temperature (mammals, birds).
- Conformers (ectotherms): internal temperature matches environment (frogs, lizards, many fish).
- Thermoregulation mechanisms: shivering, vasoconstriction, panting, sweating.
- Insulation differences: cold-climate animals have more fat/fur; hot-climate animals have less insulation and larger surface area.
- Homeostasis via negative feedback (maintain set point) and positive feedback (amplify process, e.g., childbirth via oxytocin).
Endocrine System: Glands And Hormones
- Exocrine glands: secrete through ducts (e.g., sweat glands).
- Endocrine glands: secrete hormones into blood (pituitary, thyroid, adrenal).
- Hormones: slow-acting chemical messengers binding target receptors.
- Pituitary gland: connected to hypothalamus, "master gland"; anterior and posterior lobes.
- Posterior pituitary: releases oxytocin.
- Anterior pituitary: secretes hormones regulating adrenal (ACTH), thyroid (TSH), and reproduction (FSH, LH).
- Gonads produce sex hormones: progesterone, estrogen, testosterone; regulate gamete formation.
- Female cycles: ovarian cycle (~28 days), menstrual cycle (uterine lining changes); embryo releases progesterone, estrogen, and hCG (pregnancy marker).
Digestive System: Regions And Functions
- Functions: digest/absorb nutrients, reabsorb water and salts, eliminate waste.
- Foregut: mouth, esophagus, stomach (acid and protein digestion).
- Midgut: small intestine (completes protein/carbohydrate digestion, begins fat digestion, main nutrient absorption).
- Hindgut: large intestine (water reabsorption), rectum, bladder for excretion.
- Accessory organs: pancreas (enzymes, insulin/glucagon), liver (detoxification), gallbladder (bile storage).
- Blood sugar regulation: glucagon raises blood glucose; insulin lowers blood glucose and promotes glycogen storage.
Respiratory And Circulatory Systems
- Breathing: diaphragm contracts to expand chest cavity and inhale; relaxes to exhale.
- Gas exchange in alveoli: O2 → blood, CO2 → lungs to be exhaled.
- Circulatory system transports gases, nutrients, wastes.
- Mammalian heart: four chambers separate oxygenated and deoxygenated blood.
- Cardiac circuit: lungs → pulmonary veins → left atrium → left ventricle → aorta → body → vena cava → right atrium → right ventricle → pulmonary artery → lungs.
- Cardiac cycle phases: diastole (relaxation, filling) and systole (contraction, ejection).
- Heart sounds ("lub-dub") due to atrioventricular valve closure.
- Veins carry blood to heart; arteries carry blood away.
Capillary Exchange And Pressures
- Capillaries: site of exchange for glucose, O2, CO2, solutes.
- Fluid compartments: blood plasma (in capillaries) and extravascular fluid (outside).
- Forces governing exchange: hydrostatic pressure (blood pressure) and oncotic pressure (protein osmotic pressure).
- Four opposing pressures: capillary hydrostatic, capillary oncotic, tissue hydrostatic, tissue oncotic.
- Net movement depends on combined pressures.
Neurons And Membrane Potentials
- Neuron parts: dendrites (receive signals), cell body (integrates), axon (conducts), axon terminal (transmits).
- Resting and action potentials depend on charge difference across membrane.
- Major ions: Na+ (sodium), K+ (potassium), Cl- (chloride), Ca2+ (calcium).
- Movement of ions into/out of cells changes membrane charge, triggering firing.
- Further study recommended in neurobiology resources.
Immune System
- Purpose: distinguish self from non-self and destroy pathogens.
- Innate immunity: fast, non-specific (skin, mucous, cytokines, phagocytes).
- Acquired (adaptive) immunity: slower, specific; includes humoral and cell-mediated responses.
- Humoral response: memory B cells → plasma B cells produce specific antibodies.
- Cell-mediated response: cytotoxic T cells bind and destroy infected cells.
- Both arms participate in viral defense (e.g., SARS-CoV-2).
Animal Behavior: Causes And Examples
- Proximate causes: immediate physiological mechanisms for behavior (how).
- Ultimate causes: evolutionary reasons for behavior (why).
- Fixed action patterns: innate, stereotyped behaviors completed once initiated (e.g., spider web weaving).
- Learning: behavior modification from experience (classical conditioning — Pavlov).
- Imprinting: rapid attachment during critical period (e.g., ducklings).
- Social communication example: bee waggle dance conveys food location.
- Hormonal effects: oxytocin promotes bonding and parental care.
Ecosystems, Diversity, And Trophic Cascades
- Ecosystem: organisms in habitat + physical environment.
- Community diversity metrics: richness (number of species) and evenness (relative abundance).
- Community composition changes due to colonization, extinction, natural events, human influence.
- Trophic structure: primary producers (plants) → primary consumers (herbivores) → omnivores → secondary/tertiary consumers.
- Trophic cascades: changes at one trophic level affect others due to interconnected food web dynamics.
Action Items / Next Steps
- Review key terms: prokaryote, eukaryote, peptidoglycan, endosymbiosis, gametophyte, sporophyte, phytochrome, rubisco.
- Memorize major organ systems and their primary functions.
- Practice drawing the cardiac circuit and alternation of generations cycle.
- Solve practice questions on membrane potentials and capillary exchange pressures.