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Vaccine Resurgence and Hesitancy

Sep 18, 2025

Overview

This lecture explores the resurgence of vaccine-preventable diseases, the roots of vaccine hesitancy, and challenges in public health communication and science reporting.

Vaccine Achievements and Disease Resurgence

  • Vaccines eliminated diseases like polio, smallpox, diphtheria, and nearly eradicated measles in the US.
  • Despite earlier successes, measles and whooping cough cases are rising again.
  • Over 600 measles cases were reported in the US in 2014; whooping cough outbreaks have also resurged, leading to infant deaths.

Herd Immunity and Vulnerable Populations

  • Herd immunity requires about 94% vaccination coverage for measles to prevent outbreaks.
  • Infants and those unable to be vaccinated rely on others’ immunity for protection.
  • Low vaccination rates in certain communities create pockets of vulnerability.

Origins of Vaccine Hesitancy and Myths

  • A 1998 paper by Dr. Andrew Wakefield falsely linked the MMR vaccine to autism, causing widespread fear.
  • Follow-up studies found no link between vaccines and autism, and Wakefield’s paper was retracted for unethical conduct.
  • Miscommunication about vaccine preservatives like thimerosal (ethyl mercury) further fueled concerns.

Communication Challenges and Media Influence

  • Scientific language often expresses uncertainty, which can be misinterpreted by the public and media.
  • Media reporting sometimes gives false balance by equating anecdotal experiences with scientific evidence.
  • High-profile individuals, such as Jenny McCarthy, have amplified vaccine fears through personal stories.

Community and Sociocultural Factors

  • Vaccine hesitancy is prevalent in certain educated, affluent communities and some religious/ethnic groups.
  • Public health officials are seeking new strategies to effectively communicate vaccine safety.

Research on Misinformation and Public Response

  • Studies show correcting vaccine myths reduces belief in them but may not increase willingness to vaccinate.
  • The failure of information campaigns suggests simple fact-sharing may be insufficient to change behavior.

Key Terms & Definitions

  • Herd Immunity — Protection from disease that occurs when a high percentage of a community is immunized.
  • MMR Vaccine — Immunization protecting against measles, mumps, and rubella.
  • Thimerosal — A vaccine preservative containing ethyl mercury, not linked to autism.
  • Anecdote — A personal story, not valid scientific evidence.

Action Items / Next Steps

  • Review assigned readings on vaccine safety and herd immunity.
  • Prepare to discuss case studies of vaccine hesitancy in the next class.