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Anatomy & Physiology Basics

Sep 4, 2025

Overview

This lecture introduces the basic concepts of anatomy and physiology, including structural organization, body systems, characteristics of life, homeostasis, and anatomical terminology.

Introduction to Anatomy and Physiology

  • Anatomy studies body structures and their relationships; physiology investigates body functions and processes.
  • Developmental anatomy examines structural changes from conception to adulthood; embryology focuses on the first 8 weeks.
  • Microscopic anatomy includes cytology (cells) and histology (tissues).
  • Gross anatomy studies structures visible without a microscope, by systems or regions.
  • Surface anatomy involves external observation; anatomical imaging uses technology to view internal structures.
  • Pathology studies diseases, their causes, and effects.

Subspecialties of Physiology

  • Neurophysiology studies nerve cell functions.
  • Endocrinology investigates hormones.
  • Cardiovascular physiology covers heart and vessels.
  • Immunology studies defense against diseases.
  • Respiratory, renal, and pathophysiology explore lungs, kidneys, and disease changes.

Levels of Structural Organization

  • Six levels: chemical, cell, tissue, organ, organ system, and organism.
  • Chemical: atoms and molecules; cellular: cells and organelles; tissue: groups of similar cells; organ: tissues combined; system: related organs; organism: entire living being.

Organ Systems (Mnemonic: SMILE N CURRD)

  • Skeletal, muscular, integumentary, lymphatic, nervous, cardiovascular, urinary, respiratory, reproductive, and digestive systems—each with distinct functions and components.

Characteristics of Life

  • Organization, metabolism (chemical reactions), responsiveness, growth, development (differentiation and morphogenesis), and reproduction define living organisms.

Homeostasis and Body Fluids

  • Homeostasis is maintaining a constant internal environment.
  • Intracellular fluid (inside cells) and extracellular fluid (interstitial, plasma, lymph, CSF, synovial, eye fluids).

Feedback Systems

  • Feedback loops monitor and adjust body conditions: receptors detect changes, control centers process, and effectors respond.
  • Negative feedback reverses changes (e.g., body temperature); positive feedback amplifies (e.g., childbirth).

Pathophysiology and Disease

  • Pathophysiology studies how disease disrupts normal processes due to genetics, environment, or lifestyle.

Anatomical Planes and Directions

  • Sagittal divides left/right; transverse divides top/bottom; frontal divides front/back; oblique is at an angle; median is midline.
  • Abdomen can be divided into 4 quadrants or 9 regions.

Body Sections, Regions, Cavities

  • Longitudinal, transverse, and oblique sections describe organ cuts.
  • Main regions: head, neck, trunk; limbs: upper and lower.
  • Body cavities: dorsal (cranial and vertebral), ventral (thoracic, abdominopelvic), housing major organs.

Serous Membranes and Cavities

  • Serous membranes line cavities and cover organs with parietal (wall) and visceral (organ) layers; fluid between reduces friction.
  • Pericardium (heart), pleura (lungs), peritoneum (abdominal organs); mesentery supports digestive organs.

Key Terms & Definitions

  • Anatomy — Study of body structures.
  • Physiology — Study of body functions.
  • Homeostasis — Maintenance of stable internal conditions.
  • Negative feedback — Mechanism that reverses a change.
  • Positive feedback — Mechanism that amplifies a change.
  • Serous membrane — Double-layered lining of body cavities.
  • Organ system — Group of organs with a common function.

Action Items / Next Steps

  • Review organ system functions using the SMILE N CURRD mnemonic.
  • Study anatomical planes and regions for diagram labeling.
  • Prepare for reading on tissue types and homeostatic mechanisms.