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Diffusion in Cells

Oct 9, 2025

Overview

This lecture covers the definition of diffusion, its role in and across cell membranes, and the main factors affecting its rate.

What is Diffusion?

  • Diffusion is the net movement of particles from an area of higher concentration to an area of lower concentration.
  • Particles move randomly, resulting in an overall spreading out until evenly distributed.
  • Diffusion occurs in both gases (e.g., perfume in air) and liquids (e.g., food coloring in water).

Diffusion and Cell Membranes

  • Diffusion can happen across partially permeable membranes, like cell membranes.
  • Partially permeable means only some molecules (usually small and dissolved) can pass through.
  • Small molecules such as water, glucose, and amino acids can diffuse through cell membranes.
  • Large molecules, like proteins and starch, cannot diffuse through because they are too big.
  • Diffusion is a passive process and does not require energy from the cell.

Factors Affecting the Rate of Diffusion

  • A larger concentration gradient (greater difference in concentration) increases the rate of diffusion.
  • Higher temperature gives particles more energy, making them move faster and diffuse more quickly.
  • A larger surface area allows more particles to diffuse at once, increasing the rate of diffusion.

Key Terms & Definitions

  • Diffusion — Net movement of particles from high to low concentration.
  • Net movement — Total movement of all particles considered together as a group.
  • Partially permeable membrane — A barrier that allows only certain small molecules to pass through.
  • Concentration gradient — The difference in concentration between two areas.
  • Passive process — A process that does not require energy from the cell.

Action Items / Next Steps

  • Review definitions and factors affecting diffusion for understanding and memorization.