Lecture Notes: Chapter 3 - Cell Structure and Function
Overview
- Focus on the structure and function of cells.
- Importance in understanding organs and organ systems.
Cell Membrane
- Definition: Protective outer layer of the cell.
- Composition:
- Phospholipids: Form a bilayer with hydrophilic heads and hydrophobic tails.
- Cholesterol: Provides structure and support.
- Proteins: Transmembrane proteins, glycoproteins, etc.
Functions of the Cell Membrane
- Selectively permeable to certain substances.
- Maintains concentration and electrical gradients.
- Acts as a physical barrier.
- Facilitates communication between cells.
Intracellular Environment
- Cytosol: Fluid inside cells.
- Cytoplasm: Includes cytosol, organelles, and inclusions.
Organelles
- Mitochondria: Powerhouse, produces ATP, has its own DNA.
- Endoplasmic Reticulum (ER):
- Rough ER: Protein synthesis, has ribosomes.
- Smooth ER: Lipid synthesis, lacks ribosomes.
- Golgi Apparatus: Modifies and packages proteins for secretion.
- Nucleus: Contains DNA in the form of chromatin.
Other Cell Components
- Ribosomes: Protein synthesis.
- Cytoskeleton: Provides structural support.
- Inclusions: Glycogen, lipid droplets, etc.
Cell Surface Structures
- Cilia: Moves fluid across cell surfaces.
- Flagella: Propels cells (e.g., sperm).
- Microvilli: Increases surface area for absorption.
Cell Junctions
- Gap Junctions: Allow communication and substance exchange between cells.
- Tight Junctions: Prevent passage of substances between cells.
- Anchoring Junctions: Provide structural support.
Cell Function and Processes
- Protein Synthesis: Initiated in the nucleus and completed in the cytoplasm.
- Secretion: Involves the Golgi apparatus and secretory vesicles.
- Apoptosis: Programmed cell death to prevent damage from necrosis.
Additional Concepts
- Stem Cells: Have the ability to divide and differentiate.
- Research Implications: Potential for regenerative medicine.
Reminder: Always relate how cellular structures and functions connect with larger biological systems and processes.