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Human Anatomy & Physiology Overview

Oct 2, 2025

Overview

This lecture provides a comprehensive review of human anatomy and physiology, covering all major body systems, key terminology, structural features, and essential functions for healthcare entrance exams.

Anatomical Terminology & Body Orientation

  • Anatomical terms define body parts and positions (ex: cranial=head, thoracic=chest, femoral=thigh).
  • Key directions: anterior (front), posterior (back), superior (towards head), inferior (towards feet), medial (toward midline), lateral (away from midline), proximal (closer to trunk), distal (further from trunk).
  • Body planes: sagittal (divides left/right), frontal (divides front/back), transverse (divides top/bottom).

Respiratory System

  • Main structures: nose, mouth, throat, larynx, trachea, bronchi, bronchioles, alveoli, lungs.
  • Function: exchanges oxygen and carbon dioxide; maintains blood pH.
  • Breathing in: diaphragm contracts, thoracic volume increases, air flows in; breathing out: diaphragm relaxes, air flows out.
  • Disease factors: asthma, pneumonia, bronchitis, smoking, pollution, allergies.

Cardiovascular System

  • Components: heart (4 chambers), blood vessels (arteries, veins, capillaries), blood.
  • Heart: right/left atrium and ventricle separated by septum.
  • Blood flow: heart β†’ arteries β†’ capillaries (exchange) β†’ veins β†’ heart β†’ lungs.
  • Key terms: systole (heart contracts), diastole (heart relaxes).
  • Electrical conduction: SA node, AV node, bundle of His, bundle branches, Purkinje fibers.
  • Functions: transports Oβ‚‚ and nutrients, removes waste, maintains blood pressure and temperature, transports hormones.

Digestive System

  • Structures: mouth, esophagus, stomach, small intestine, large intestine, rectum; accessory organs: teeth, tongue, liver, gallbladder, pancreas.
  • Function: digests food, absorbs nutrients, eliminates waste.
  • Main enzymes/hormones: gastrin, cholecystokinin (CCK), secretin, insulin, glucagon, bile.

Nervous System

  • Divisions: central (brain, spinal cord) and peripheral (nerves).
  • Neuron structure: cell body, dendrites, axon, myelin sheath, synapses.
  • Sensory (afferent) vs. motor (efferent) neurons; somatic (voluntary) vs. autonomic (involuntary) systems.

Muscular System

  • Types: skeletal (voluntary, striated), cardiac (heart, involuntary), smooth (organs, involuntary).
  • Function: movement by contraction; nerves stimulate muscles to contract.

Reproductive System

  • Male: testes, epididymis, vas deferens, seminal vesicles, prostate, penis (produce and deliver sperm).
  • Female: ovaries, fallopian tubes, uterus, vagina, vulva (produce eggs, support fetus).
  • Hormonal regulation: GnRH, FSH, LH, testosterone, estrogen, progesterone.

Integumentary System

  • Main parts: skin (epidermis, dermis, subcutaneous), hair, nails, sweat glands.
  • Functions: protection, temperature regulation, sensation, excretion.

Endocrine System

  • Glands: pituitary, thyroid, parathyroid, thymus, adrenal, pancreas, testes, ovaries.
  • Functions: hormone secretion for growth, metabolism, reproduction, mood.
  • Hormone types: lipid-based, non-polar fat-soluble, water-soluble.
  • Homeostasis via positive (oxytocin) and negative (insulin) feedback.

Urinary System

  • Structures: kidneys (cortex, medulla), ureters, bladder, urethra.
  • Function: filters blood, regulates fluid/electrolyte balance, removes waste (urine).
  • Nephron: filtration unit (includes glomerulus and tubule).
  • Kidneys produce erythropoietin for red blood cell production.

Immune System

  • Defenses: innate (skin, mucous membranes, inflammatory response) and adaptive (lymphatic system, WBCs, antibodies).
  • Cell types: phagocytes, antigen-presenting cells, helper/cytotoxic T cells, B cells, memory cells.
  • Immunity: passive (antibodies from another) vs. active (your own antibodies).

Skeletal System

  • Bone types: long (limbs), short (wrists, ankles), flat (ribs, sternum), irregular (vertebrae).
  • Bone structure: compact, spongy, marrow (produces blood cells).
  • Joints held by ligaments; muscles attach via tendons.
  • Works with muscular system for movement.

Key Terms & Definitions

  • Anterior β€” front of the body
  • Posterior β€” back of the body
  • Alveoli β€” air sacs in lungs for gas exchange
  • Systole β€” heart contraction phase
  • Diastole β€” heart relaxation phase
  • Neuron β€” basic nerve cell
  • Hormone β€” chemical messenger released by glands
  • Nephron β€” kidney’s functional unit for filtration
  • Antigen β€” substance provoking immune response

Action Items / Next Steps

  • Review anatomical terminology and body planes.
  • Memorize major organ structures and their functions within each body system.
  • Study key hormones and their roles.
  • Prepare for exam questions on system interrelationships (e.g., cardiovascular and urinary).
  • Complete assigned readings or practice questions as directed by your instructor.