🫁

Lung and Respiratory Conditions Overview

Sep 16, 2025

Overview

This lecture covers key points about lung cancer risk factors and prevention, flu precautions and treatment, asthma pathophysiology and management, and an in-depth case study on pneumonia assessment and care.

Lung Cancer: Risk Factors & Prevention

  • Smoking is the main risk factor for lung cancer; others include COPD, obesity, and inhaled irritants.
  • Prevention focuses on smoking cessation and using protective filters or masks when exposed to chemicals/irritants.
  • Treatment involves chemotherapy, radiation (including brachytherapy), and/or surgical removal (e.g., lobectomy via thoracotomy).
  • Post-surgical care includes monitoring the incision and possible chest tube management.

Influenza (Flu): Precautions & Management

  • Flu is transmitted via droplets; wear a surgical mask within 3–6 feet of the patient.
  • Test specimens for flu are often kept on ice before lab analysis.
  • Antivirals are effective within 48 hours but often have significant side effects.
  • Pneumonia is a serious complication of the flu.
  • Prevention includes annual vaccination, hand hygiene, and avoiding crowds.
  • Avian flu (H5N1) requires airborne precautions due to high contagion and potential lethality.

Asthma: Pathophysiology & Case Study

  • Asthma is characterized by bronchospasm, airway edema (swelling), and increased mucus production.
  • Peak flow meters help patients monitor airflow and recognize when to adjust treatment before symptoms worsen.
  • Acute asthma assessment focuses on respiratory rate, oxygenation, accessory muscle use, and signs of distress.
  • ABGs (arterial blood gases): low SaO2/PaO2 and high PaCO2 indicate impaired gas exchange and risk for respiratory failure.
  • Treatments include bronchodilators (e.g., albuterol), anticholinergics (e.g., ipratropium), and corticosteroids (e.g., fluticasone).
  • Inhaler use: bronchodilators are taken first, followed by other medications for better effectiveness.
  • Proper inhaler technique is essential; use spacers if coordination is an issue, and rinse mouth after steroid inhalers.

Pneumonia: Clinical Assessment & Management

  • Pneumonia causes excess fluid in the lungs and is identified by consolidation (decreased air movement from fluid/inflammation).
  • Can be bacterial, viral, or from inhaled irritants; may be community or hospital acquired.
  • Vaccination is recommended for those 65+ years old.
  • Clinical assessment includes history, oxygen saturation, use of accessory muscles, breath sounds (e.g., crackles, diminished sounds), and respiratory distress.
  • Lab findings: elevated WBCs, bands, and neutrophils indicate infection; high CO2 and low PaO2/SaO2 signal impaired gas exchange.
  • High lactate indicates anaerobic metabolism due to hypoxia.
  • Common interventions: oxygen, bronchodilators, steroids, antibiotics, antipyretics, and anxiety management.

Key Terms & Definitions

  • Bronchospasm — sudden constriction of the muscles in the walls of the bronchioles.
  • Edema — swelling caused by fluid accumulation.
  • Peak flow meter — device that measures maximum speed of exhalation to monitor asthma.
  • SaO2 (arterial oxygen saturation) — percentage of hemoglobin binding sites in the bloodstream occupied by oxygen.
  • PaO2 — partial pressure of oxygen dissolved in plasma (normal: 80-100 mm Hg).
  • PaCO2 — partial pressure of carbon dioxide in plasma (normal: 35-45 mm Hg).
  • Consolidation — solidification of lung tissue due to accumulation of fluid, often seen in pneumonia.
  • Bands — immature neutrophils, increased in acute infection.
  • Respiratory failure — inadequate gas exchange (low O2, high CO2).

Action Items / Next Steps

  • Review chest tube care and thoracotomy for next week.
  • Practice interpreting ABGs and reviewing inhaler techniques.
  • Complete reading and case studies assigned in Brightspace.
  • Prepare for continued discussion of pneumonia and respiratory failure management.