Understanding the Cell Membrane Structure

Aug 29, 2024

Cell Membrane

Overview

  • Comprised of four main components:
    1. Phospholipid Bilayer
    2. Membrane Proteins
    3. Carbohydrates
    4. Cholesterol

Phospholipid Bilayer

  • The majority component of the cell membrane.
  • Dictates cell membrane function and properties.
  • Made up of amphipathic molecules (have both polar and non-polar regions).
    • Polar Heads: Hydrophilic, face the water.
    • Non-polar Tails: Hydrophobic, face away from water.
  • Naturally forms a spherical shape due to its amphipathic nature.

Membrane Proteins

  • Embedded within the phospholipid bilayer.
  • Serve various functions such as:
    • Transport: Assists in the movement of chemicals and materials.
    • Signaling: Involves in cell signaling mechanisms.

Carbohydrates

  • Present on the outer surface of the cell membrane.
  • Function: Used for cell-to-cell recognition, helping in identifying the identity, type, and origin of cells.

Cholesterol

  • Embedded within the phospholipid bilayer.
  • Function: Provides fluidity and stability to the cell membrane.
  • Analogous to adding salt to water to change boiling/freezing points.

Selective Permeability of the Phospholipid Bilayer

  • Small, non-polar, electrically neutral molecules can pass through the bilayer.
    • Example: Steroids
  • Proteins: Generally too large to pass through.
  • Lipids: Can pass through due to being non-polar.
  • Ions: Electrically charged, repelled by the non-polar bilayer.
  • Water: Does not easily pass due to its polar nature.
  • Carbohydrates: Polar and large, do not pass easily.

Conclusion

  • The phospholipid bilayer's selective permeability allows only certain molecules to pass through, influencing cellular operations.
  • Other forms of transport will be covered in the next videos, including diffusion and additional methods that allow water and carbohydrates to pass through the membrane.