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Exploring Thymus Rejuvenation in Medicine
Sep 6, 2024
New Frontiers in Functional Medicine Podcast
Podcast Overview
Established in 2015.
Over 200 episodes, 2 million listens.
Focus: Functional medicine, epigenetics, longevity.
Goal: Actionable content for clinicians, interesting for general audience.
Acknowledgment of sponsors: Biotics Research, Rupa Health, Integrative Therapeutics.
Access full transcripts and additional resources at drcarofitzgerald.com.
Guest: Dr. Greg Fahey
Renowned cryobiologist and chief science officer at Intervene Immune.
Pioneer in thymus regeneration and age-related immune decline treatments.
Led the TRIM study on thymus rejuvenation and epigenetic age reversal.
Key Discussion Points
Thymus Rejuvenation and Age Reversal
2019 Publication
: Evidence of biological age reversal using epigenetic clocks (Horvath clock).
TRIM Study
: Demonstrated thymus rejuvenation, reversal of human epigenetic age.
TRIM-X Studies
: Follow-up studies to reproduce and expand original results.
Key Findings
:
Reversal found in multiple aging clocks.
Correlation with reduced cancer risk and mortality.
Physiological improvements like VO2 max increase, hair darkening.
Treatment Protocol
Components
: Human growth hormone, DHEA, metformin, vitamin D, zinc.
Individualized Dosing
: Adjustments based on personal biology and response.
Challenges
:
Balancing hormone levels, particularly for women.
Managing potential side effects.
Research and Development
AI and Expert System
: Developing systems to automate treatment adjustments.
Commercial Expansion
: Plans to offer treatment as a medical service in the UK.
Future Directions
Potential for Autoimmunity and Transplant Rejection Therapy
:
Thymus can be reprogrammed to treat these conditions.
Current focus on developing this approach in animal models.
Additional Studies and Trials
: Continuing to refine and expand therapeutic protocols.
Future Topics
Impact of diet, nutrition, and exercise on longevity and health.
Call to Action
Consider leaving a like or review for the podcast.
Follow ongoing research and updates at drcarofitzgerald.com.
Sponsors Acknowledgment
Thanks to Rupa Health, Biotics, Integrative Therapeutics, Timeline, and OneSkin for their support.
📄
Full transcript