Understanding Flehmen Response in Mammals

Apr 28, 2025

Flehmen Response

Definition

  • The flehmen response involves an animal curling its upper lip back to expose its front teeth, inhaling with nostrils closed, and holding this position for several seconds.
  • Also known as flehmen position, flehmen reaction, flehmen grimace, or flehming.

Origin

  • The term "flehmen" comes from the German verb flehmen, meaning "to bare the upper teeth".
  • First introduced in 1930 by Karl Max Schneider, a director at the Leipzig zoo.
  • Initially described by Frederik Ruysch in 1732 and Ludwig Jacobson in 1813.

Function and Mechanism

  • Purpose: Transfers pheromones and other scents into the vomeronasal organ (VNO or Jacobson's organ), aiding in scent detection.
    • The VNO is an auxiliary olfactory sense organ crucial for processing chemical signals.
  • Mechanism: Involves drawing air into the VNO via a duct behind the front teeth.
  • Organ Development: Well-developed in mammals like cats and horses.

Chemical Cues

  • Detects non-volatile organic compounds (non-VOCs), such as pheromones and hormones from the animal's genital regions or urine.

Occurrence

  • Exhibited by a wide range of mammals, including ungulates and felids.
  • Common in domestic cats and horses.
  • In horses, it may indicate discomfort if occurring outside typical contexts.

Intra-species Communication

  • Reproductive Status: Used by males to identify reproductive states of females via pheromones.
  • Reproductive Synchrony: Synchronizes reproductive events among females, e.g., in sable antelope and American bison.
  • Post-parturition: Seen in mares after birth, reacting to newborn foals and amniotic fluids.
  • Immature Animals: Young animals such as horses and elephants perform flehmen, indicating early VNO maturity.

Inter-species Communication

  • Response to Various Species: Tested in goats with urine from 20 different species, indicating an interspecific pheromone trigger.
  • Observed in a range of mammals, including domestic cats, giraffes, elephants, and more.

Notable Observations

  • Horses: Strong response to odors from mares in estrus.
  • Giraffes: Includes urine tasting as part of the response.
  • Elephants: Use trunk "finger" to transfer stimuli to VNO.