Lecture on Cancer Treatment and Immunotherapy

Introduction

• The cure for cancer is becoming a reality.
• Importance of understanding the growth of cancer cells and immune system's role.
• Not all patients respond to immunotherapy; exploring reasons.

Cancer Growth

• Tumors grow exponentially once a blood vessel touches them.
• Example: 1 cm breast cancer = 1 billion cancer cells.
• Cancer cells multiply rapidly, demanding blood supply.

The Role of Immune System

• Body's natural defense against diseases, including cancer.
• Immunotherapy: Varied patient responses.
  • Single bacterium, Akkermansia muciniphila, found in responders.
  • Lab tests showed transferring this bacteria helped mice respond to therapy.

Growing Akkermansia Muciniphila

• Foods that promote growth:
  • Pomegranate juice/seeds
  • Cranberries and their juice
  • Concord grapes/juice
  • Chili peppers
  • Chinese black vinegar

Obesity and Cancer Risk

• Excess body fat increases cancer risk.
• Study shows higher breast cancer risk in women with excess body fat.
• Inflammation from 'skinny fat' linked to cancer growth.
• Visceral fat linked to 14 other cancers.

Angiogenesis and Cancer

• Angiogenesis: Growth of blood vessels, vital in cancer growth.
• Tumors hijack blood vessels to sustain themselves.
• Anti-angiogenic foods:
  • Coffee and tea

Studies on Tea and Cancer

• Research on various teas and their health benefits.
• Surprise finding: Earl Grey tea supports healthy circulation.
• Matcha: High in polyphenols, fibrous, kills cancer stem cells.

Technological Advances in Cancer Treatment

• AI and machine learning in identifying cancer mutations.
• Development of personalized cancer vaccines.
• Clinical trials showing promise in treating brain cancer like glioblastoma.

Summary

• Diet and lifestyle have significant roles in cancer prevention.
• Immune system and angiogenesis critical in cancer treatment.
• Continued research and trials vital for breakthroughs.