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Understanding Abdominal Cutaneous Nerve Entrapment

Apr 17, 2025

Abdominal Cutaneous Nerve Entrapment Syndrome (ACNES)

Introduction

  • ACNES is a common cause of abdominal pain often overlooked and misdiagnosed as intra-abdominal disorders.
  • Misdiagnosis can lead to unnecessary consultations, tests, and surgeries, with significant financial costs.
    • Example: Greenbaum (1999) estimated $914 per patient; Thompson et al. (2001) noted $6,727 on average per patient.
  • Frequently misdiagnosed as psychiatric conditions like anxiety, depression, or hysteria.

Pathophysiology of ACNES

  • Peripheral nerve entrapment occurs at sites where nerves change direction, enter tunnels, or pass over bands, causing irritation and swelling.
  • Muscle contraction may compress or traction on nerves, causing further injury.
  • Entrapment leads to localized swelling, possibly compromising nerve circulation.

Anatomy Pertinent to ACNES

  • Thoracoabdominal nerves terminate as cutaneous nerves anchored at six points: spinal cord, posterior, lateral, anterior branches, accessory branches, and skin.
  • Most common entrapment site: lateral border of the rectus abdominis muscle.
  • Nerve vascular bundle can herniate through fibrous ring, causing compression and ischemia.
  • Maneuvers increasing abdominal pressure can exacerbate the condition.

Diagnosing ACNES

Clinical Presentation

  • Symptoms: localized, dull or burning pain, sometimes with a sharp component.
    • Acute pain often occurs at night but doesn’t prevent patients from working the next day.
    • Pain radiates with movement; lying down may help or worsen it.
  • Common misdiagnoses: ovarian disorders in women, hernia or ulcer in men.
  • Carnett’s sign: differentiates between abdominal wall pain and intra-abdominal pain.

Physical Examination

  • Key: accurately identify the tender spot by palpation.
  • Carnett’s sign to distinguish source of pain.
  • Pinch test and electromyographic studies used to confirm diagnosis.
  • Injection of local anesthetic can help confirm diagnosis.

Recommended Treatment for ACNES

  • Local anesthetic injection into the muscular channel can relieve pain.
    • Technique is critical; needle should not be inserted too deeply.
    • Sequential injections may be needed for persistent cases.
  • Other treatments include ice application, elastic bandage, or heat.
  • Corticosteroids may be used, but caution is advised due to potential pain and atrophy.

Summary and Conclusions

  • Pain in the abdominal wall is often misdiagnosed as intra-abdominal pain.
  • ACNES is commonly caused by nerve entrapment at the lateral border of the rectus muscle.
  • Diagnosis and treatment involve local anesthetic injections.
  • Early recognition and treatment can prevent unnecessary tests and surgeries.
  • Clinicians should monitor ACNES patients closely and evaluate for visceral diseases if no improvement.

Practice Tips:

  • Use local anesthetic injections for diagnosis/treatment.
  • Encourage precise location of pain from patients.
  • Consider nerve entrapment in cases of unexplained abdominal wall pain.
  • Apply ice or heat to alleviate symptoms.