❤️

5.4 Neurogenic shock

Mar 8, 2025

Cardiovascular System and Neurogenic Shock

Cardiovascular System Overview

  • Heart: Central organ of the system.
  • Arteries: Deliver oxygenated blood from the heart to the organs.
  • Veins: Return deoxygenated blood from the organs to the heart.

Neurogenic Shock

  • Definition: A type of shock where the nervous system stops functioning properly.
  • Causes:
    • Trauma (e.g., spinal cord injury).
    • Epidural issues causing nerve damage.
  • Mechanism:
    • Loss of sympathetic tone.
    • Leads to pooling of peripheral blood.

Vascular Tone and Blood Flow

  • Sympathetic Tone: Maintains vascular tightness and is critical for blood pressure.
    • Similar to muscle flexing for tightness.
  • Trampoline Analogy: Taut trampolines allow better bouncing akin to vascular tone maintaining blood flow.
  • Loss of Tone:
    • Blood vessels become floppy (arteries and veins).
    • Reduced blood flow to organs.
    • Blood pooling in venous system.

Impact on Cardiovascular Function

  • Decreased Systemic Vascular Resistance:
    • Lower blood pressure and tissue perfusion.
  • Cardiac Output:
    • Dependent on stroke volume and heart rate.
    • Decreased blood return reduces stroke volume.
    • Reduced cardiac output decreases blood pressure further.
  • Heart Rate:
    • Controlled by the sympathetic nervous system.
    • Loss of input causes bradycardia.

Symptoms of Neurogenic Shock

  • General Symptoms:
    • Altered mental status.
    • Decreased urine output.
    • Overall organ dysfunction.
  • Specific to Neurogenic Shock:
    • Bradycardia (unique among shock types).
    • Warm skin due to vessel dilation affecting blood distribution.

Treatment of Neurogenic Shock

  • Pressers:
    • Medications to restore vascular tone by clamping blood vessels.
  • IV Fluids:
    • Increase vascular fluid volume to maintain blood flow.
  • Atropine:
    • Blocks parasympathetic action, enhances "fight or flight".
    • Increases heart rate and cardiac output.