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Cardiac Cycle Overview

Sep 16, 2025

Overview

This lecture explains the pressure, volume, heart sounds, and EKG changes during the cardiac cycle, focusing on the left side of the heart.

The Cardiac Cycle Pressure Graph

  • The graph illustrates pressure changes in the left atrium, left ventricle, and aorta over time.
  • Left ventricular pressure rises sharply during systole, exceeding aortic pressure to open semilunar valves.
  • Atrial contraction causes a small bump in atrial pressure, pushing blood into the ventricle.
  • AV valves close when ventricular pressure exceeds atrial pressure, causing the first heart sound ("lub").
  • Semilunar valves close when aortic pressure exceeds ventricular pressure, causing the second heart sound ("dub").
  • The dicrotic notch is a small dip in aortic pressure as blood rebounds against closed semilunar valves.

Phases of the Cardiac Cycle

  • Isovolumetric contraction: all valves closed, ventricular pressure rises but no blood flows.
  • Ejection phase: ventricular pressure exceeds aortic pressure, semilunar valves open, and blood is ejected.
  • Isovolumetric relaxation: all valves closed, ventricular pressure falls until it equals atrial pressure.
  • AV valves open once ventricular pressure drops below atrial pressure, allowing passive filling.

Heart Sounds and Valve Status

  • "Lub" (S1): closure of AV (atrioventricular) valves at the start of ventricular systole.
  • "Dub" (S2): closure of semilunar valves at the start of ventricular diastole.
  • Dicrotic notch occurs just after semilunar valve closure in the aortic pressure curve.

Volume and EKG Relationships

  • Ventricular volume decreases as pressure rises and blood is ejected.
  • The QRS complex on the EKG represents ventricular depolarization, leading to contraction and decreasing volume.
  • Volume is lowest in the ventricle after blood ejection when pressure is highest.

Key Terms & Definitions

  • Atrial Systole — contraction of the atrium, pushing blood into the ventricle.
  • Ventricular Systole — contraction of the ventricle, ejecting blood into the aorta.
  • AV Valves — atrioventricular valves separate atria from ventricles; close for the "lub" sound.
  • Semilunar Valves — valves at the base of the aorta and pulmonary trunk; close for the "dub" sound.
  • Isovolumetric Phase — period when all heart valves are closed and volume in the ventricles stays the same.
  • Dicrotic Notch — small dip in aortic pressure due to the rebound of blood against the closed semilunar valves.
  • QRS Complex — part of the EKG representing ventricular depolarization.

Action Items / Next Steps

  • Practice interpreting pressure, volume, and EKG graphs for the cardiac cycle.
  • Review the phases and corresponding valve events in the cardiac cycle.
  • Prepare for the next topic on cardio dynamics.