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Overview of Biomolecules and Their Functions

May 6, 2025

Chapter 09: Biomolecules

What are Biomolecules?

  • Definition: Chemicals or molecules present in living organisms.
  • Types:
    • Inorganic: Includes minerals, gases, and water.
    • Organic: Includes carbohydrates, fats, proteins, nucleic acids, vitamins.

Classification of Biomolecules

  • Chemical Forms: Aldehyde, Ketones, and Aromatic compounds.
  • Biochemical Forms: Amino acids, Nucleotides, and Fatty acids.

Macromolecules

  • Formation: Except lipids, they are formed by polymerization of monomers.
  • Proteins:
    • Polymers of amino acids.
    • Linked by peptide bonds formed between COOH group of one amino acid and NH3 group of the next with the removal of H2O.
  • Nucleic Acids:
    • Phosphate molecules link 3 C of sugar of one nucleoside to the 5 C of sugar of next nucleosides.
    • Forms 3-5 phosphodiester bond releasing two water molecules.
  • Polysaccharides:
    • Monosaccharides linked by glycosidic bonds formed by dehydration between two carbon atoms of two adjacent monosaccharides.

Carbohydrates (Polysaccharides)

  • Structure: Long chains of sugars with different monosaccharides as building blocks.
  • Starch:
    • Present in plants as an energy storehouse.
    • Forms helical secondary structure.
    • Can hold I2 molecules in its helical structure.
  • Cellulose:
    • Composed of glucose molecules joined by 1-4 linkages.
    • Most abundant organic molecule on Earth.
  • Glycogen:
    • Known as animal starch.
    • Reserve food material for animals, bacteria, and fungi.
    • Glucose molecules arranged in highly branched bush-like chain with two types of linkages: 1-4 in straight chain and 1-6 in branching.

Proteins

  • Structure: Polypeptide chains made up of 20 types of amino acids.
  • Bonds: Joined together by peptide bonds between amino and carboxylic groups.
  • Types of Amino Acids:
    1. Essential Amino Acids: Obtained from food by living organisms.
    2. Non-essential Amino Acids: Can be synthesized by the body from raw materials.
  • Functions of Proteins:
    1. Transport nutrients across membranes.
    2. Fight against infectious organisms.
    3. Produce enzymes and proteins.

End of Chapter 09: Biomolecules