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Basics of Genetics and Inheritance

May 4, 2025

Introduction to Genetics - Miss Angler's Biology Class

Introduction

  • Welcome to an introduction to genetics.
  • New content is posted every Tuesday and Thursday for grades 8-12.
  • Membership offers exclusive videos, live lessons, and Q&A sessions.

Overview of Genetics

  • Purpose: Introduction to basic genetics concepts.
  • Detailed content available in the Grade 12 playlist on topics like monohybrid and dihybrid crosses, sex-linked disorders, etc.

Basics of Chromosomes

  • Every cell has a chromatin network found in the nucleus.
  • During cell division (meiosis or mitosis), the chromatin network condenses into chromosomes.
  • Chromosome: A collection of DNA (humans have 46 chromosomes).
  • DNA is the code of life, responsible for protein coding.

Genes and Alleles

  • Gene: Section of DNA coding for a specific characteristic (e.g., height, hair color).
  • Physical traits expressed by genes are called phenotypes.
  • Allele: Variation of a gene (e.g., blue-eyed allele, brown-eyed allele).
  • Homologous chromosomes carry alleles for the same genes.

Inheritance

  • Humans have 46 chromosomes forming homologous pairs.
  • Chromosomes are inherited from parents (maternal from mother, paternal from father).
  • Each individual has two alleles for every gene, one from each parent.
  • During meiosis, maternal and paternal chromosomes separate, passing only one allele.

Dominant and Recessive Alleles

  • Dominant Alleles: Represented by a capital letter (e.g., B). They mask recessive alleles.
  • Recessive Alleles: Represented by a lowercase letter (e.g., b). Require two for the trait to be expressed.

Genotypes and Phenotypes

  • Genotype: Genetic makeup of an individual.
  • Phenotype: Physical expression of genes.
  • Genotype examples:
    • Homozygous Dominant: Two capital letters (BB).
    • Heterozygous: One capital and one lowercase letter (Bb).
    • Homozygous Recessive: Two lowercase letters (bb).

Terminology Recap

  • Chromatin Network: DNA structure visible during interphase.
  • Chromosomes: Structures carrying DNA.
  • Genes: DNA segments coding for traits.
  • Alleles: Variations of a gene.
  • Dominant/Recessive Alleles: Determine which traits are expressed.
  • Homozygous/Heterozygous: Refers to allele pairings.

Conclusion

  • Regular updates on the channel with new content.
  • Encourage participation in membership for additional support.