Overview
This overview addresses RAD 140, a selective androgen receptor modulator (SARM), covering its intended use, benefits, drawbacks, recommended use cases, and practical advice on dosing and stacking.
What is RAD 140 and Its Intended Use
- RAD 140 is a SARM designed to bind specifically to the androgen receptor in muscle tissue to promote muscle growth.
- Developed as a potential testosterone replacement therapy with reduced side effects compared to exogenous testosterone.
- Intended to deliver benefits such as improved muscle mass, fat loss, enhanced recovery, and better physical performance.
Benefits and Use Cases
- Used for building and preserving muscle, especially during calorie deficits or cutting phases.
- Provides anti-aging benefits by helping older adults retain muscle mass and strength.
- Boosts athletic performance, recovery, and workout capacity.
- Suitable for those seeking testosterone replacement without typical testosterone side effects (e.g., estrogenic effects, DHT-related issues).
- Used by bodybuilders bridging between steroid cycles, and by "naturals" breaking muscle gain plateaus.
Safety, Side Effects, and Concerns
- Generally well-tolerated with minimal serious side effects reported in anecdotal and clinical experiences.
- Rare reports of liver issues, though not seen consistently in lab testing; liver support supplements (TUDCA, NAC) are suggested especially at higher doses.
- Causes testosterone suppression primarily through replacement rather than inhibition; may be managed with testosterone boosters if necessary.
- May cause increased mental energy, which could rise to anxiety in some individuals.
- Legal to purchase and use, but banned in competitive sports due to performance-enhancing effects.
Mechanism of Action and Stacking Recommendations
- Acts via the androgen receptor in muscle, similar to testosterone but with tissue selectivity.
- Can be effectively stacked with compounds affecting other muscle-building pathways (e.g., MK-677 for growth hormone, insulin mimetics).
- Stacking enhances synergy in muscle growth beyond RAD 140 alone.
Purchasing, Legality, and Community Feedback
- Widely available, inexpensive compared to many supplements (≈$60 for a 60-day supply at 10mg/day).
- Not currently FDA approved, but expected to gain approval and become more expensive once prescribed medically.
- Positive community and anecdotal feedback, though negative reports may result from contaminated or mislabeled products.
Recommendations / Advice
- Consider liver support if using higher doses or engaging in intense training.
- Evaluate product sources carefully to ensure quality and authenticity.
- For younger adults or those concerned about fertility, alternative SARMs like AC262 may be preferable for lower side effect risk.
- Monitor lab work if using for extended periods, especially regarding hormone and liver panels.