Transcript for:
Bacitracin Overview and Use

hey everybody dr. role this figure on to talk about the bacitracin so bacitracin is a called a peptide antibiotic so peptides to be short protein chains the reason it's called bacitracin it was originally isolated from bacillus subtilis oral organism from an actual wound from a patient named Tracy so that's actually just come interesting where the name bacitracin comes from so it's a little different it does block the production of cell wall but doesn't a different way it doesn't actually interfere with the production of the cell wall so much as the movement so cell wall pieces of cell wall are going to be produced inside the cell and then moved out to the cell same way cell membranes are made so this drug is actually going to block the movement of the precursors the peptidoglycan cell wall precursors from making it to where they're produced to the actual cell wall so it is going to inhibit the function of the cell for the production of new cell wall which will kill the bacteria when they don't have a good enough cell wall basically osmosis will kill them at this point the cell wall can't protect them if it's too weak all right it is it is a broad-spectrum antibiotic is effective against both gram positives and grand negatives one of the primary use though would be against gram-positive skin organisms like Staphylococcus streptococcus so you technically could use it orally or intramuscularly and occasionally it is but it is nephrotoxic meaning can damage the kidneys so it's primarily used with polymyxin B and neomycin in what you would call the triple antibiotic or most commonly known by the brand name neosporin so this is this would primarily be used topical in that way so this neomycin I have to think for a second neomycin polymyxin B and that's a tracing are the three antibiotics in your triple antibiotic ointment or your neosporin all right so that is bacitracin that's primarily how it's used and that's what it does hope this helps I have one would I be blessed