Hi, I'm Cathy with Level Up RN.
In this video we are going to be talking about MAOIs or monoamine oxidase
inhibitors. And at the end of the video, I'm going to give you guys a little quiz to test
your knowledge of some of the key points we'll be covering. So definitely stay tuned for that.
And if you have our Level Up RN, psychiatric mental health nursing flashcards definitely pull
out your flashcards so you can follow along with me. And pay close attention to the bold red text
on this flashcard because MAOIs are highly tested on in nursing school and those bold red items
are likely to show up on a nursing school exam. Anyways include medications such as
phenelzine, tranylcypromine, isocarboxazid, as well as selegiline. And these medications work
by inhibiting the enzyme monoamine oxidase which causes an increase in neurotransmitters such
as norepinephrine, serotonin, and dopamine. Key side effects include anxiety, agitation,
orthostatic hypotension, and the risk for a hypertensive crisis. That is definitely the
most important side effect to remember when it comes to MAOIs. Our cool chicken hint to help
you remember this is please take it seriously. Phenelzine, tranylcypromine, isocarboxazid,
and selegiline can cause a hypertensive crisis. It's also super important to know that if
your patient consumes foods that are rich in tyramines when they're taking an MAOI,
this can result in a hypertensive crisis. So foods that are rich in tyramines include
avocados, bananas, aged cheese, pepperoni, and salami, red wine, and chocolate. So a lot of
the finer things in life. So our little rhyme to help you remember this fact is with phenelzine
you can't enjoy life's finer things because they contain tyramines. In addition to teaching
your patient to avoid foods rich in tyramines, you should also teach your patient that MAOIs
interact with many other medications including over-the-counter cold medications. And this
interaction can lead to a hypertensive crisis. If your patient wants to switch from an MAOI to
another antidepressant, a two-week washout period is necessary between the time they discontinued
the MAOI and before they start their new medication. All right, it's time for a quiz, and
I've got three questions for you. Question number one, consuming foods rich in blank can cause a
hypertensive crisis in a patient taking an MAOI. The answer is tyramines. Question number
two, this is a multiple-choice question. Which of the following snacks would be appropriate
for someone taking fennel phenelzine? A, Cheddar cheese and crackers. B, chips and guacamole. C,
cereal with milk. Or D, a pepperoni pizza slice. The answer is C, cereal with milk. All the other
options are high in tyramines. Question number three, a patient taking an MAOI can safely
use a decongestant for a cold. True or false. The answer is false. So MAOIs interact
with many other medications including many cold or cough medications. So
the patient will need to check what their provider first before taking
any other medication. All right, that is it for this video. I hope you found it
helpful. Take care and good luck with studying.