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AP Biology Comprehensive Last-Minute Review

May 4, 2025

AP Biology Last-Minute Review

General Tips for AP Biology Test

  • Format:
    • Total time: 3 hours, divided into two parts (90 minutes each)
    • Part 1: 60 multiple choice questions
    • Part 2: Six free-response questions (FRQs), including 2 long and 4 short questions
    • Both sections are weighted equally (50% each)
  • Test Day Essentials:
    • Bring: 2 blue/black pens, 2 number 2 pencils, a calculator (non-internet)
    • Provided: formula sheet and extra paper
    • ID required if not taking at your school
    • Do not bring phones, smartwatches, tablets, or cameras
  • Answering Strategies:
    • Multiple Choice: Answer all, guess if unsure (no penalty for wrong answers)
    • Use 1 minute per question to leave time for review
    • FRQs: Write in complete sentences, avoid bullet points unless specified
    • Prioritize long FRQs as they carry more points

Content Review

Important Topics

  • Natural Selection & Evolution: Commonly appears, review thoroughly
  • Genes & Proteins:
    • Cells have unique genomes
    • Genes code for proteins, not all genes are expressed in every cell
    • Signal transduction pathways: involve signal, transduction, and response
  • Protein Synthesis:
    • RNA polymerase synthesizes mRNA, eukaryotic transcription and translation occur separately
    • Prokaryotic transcription is coupled with translation
  • Gene Regulation:
    • Operons (e.g., lac operon in prokaryotes)
    • Eukaryotic regulation through RNA processing (introns/exons)

Molecular Biology and Genetics

  • Biological Macromolecules:
    • Structure and monomers (nucleic acids, proteins, carbohydrates, lipids)
    • Proteins: chains of amino acids, function affected by shape
  • Cellular Respiration & Photosynthesis:
    • Cellular respiration: glycolysis, Krebs cycle, oxidative phosphorylation (Oxygen as final electron acceptor)
    • Photosynthesis: light-dependent reactions and Calvin cycle in chloroplasts
    • Endosymbiosis theory for mitochondria and chloroplasts

Feedback Loops

  • Negative Feedback:
    • Maintains homeostasis (e.g., blood sugar, temperature)
  • Positive Feedback:
    • Amplifies changes (e.g., childbirth contractions)

Cellular Structures

  • Cell Membranes:
    • Phospholipid bilayer, proteins, carbohydrates
    • Control of substance passage, cell communication
  • Mitochondria & Chloroplasts:
    • Sites of cellular respiration and photosynthesis, have own DNA (endosymbiotic origin)

Ecology and Environment

  • Energy and Metabolism:
    • Endotherms and ectotherms regulate body temperature differently
    • Energy pyramids: energy loss at each trophic level
  • Ecological Relationships:
    • Impact of biodiversity and resilience in ecosystems

Evolution & Inheritance Patterns

  • Hardy-Weinberg Principle:
    • Used to determine allele frequencies in non-evolving populations
    • Know formulas: p + q = 1, p^2 + 2pq + q^2 = 1
  • Patterns of Inheritance:
    • Single gene, dihybrid, sex-linked, genetically linked, mitochondrial inheritance

Exam Strategies & Math

  • Graphing & Data Interpretation:
    • Use appropriate graph types (line, bar)
    • Interpret error bars for statistical significance
  • Important Mathematical Concepts:
    • Chi-square test for genetic predictions
    • Familiarity with key equations: Hardy-Weinberg, water potential

Additional Resources

  • Refer to the channel's resources for detailed content, study plans, and exam strategies.

This review provides a comprehensive summary of key concepts and strategies for the AP Biology exam. Good luck and make sure to review your study materials for detailed insights into specific topics!