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Tricyclic Antidepressants
Jul 12, 2024
Tricyclic Antidepressants
Overview
Presenter
: Cathy with Level Up RN
Topics
: Tricyclic Antidepressants (TCAs)
Medications
: Amitriptyline, Imipramine
Uses
:
Depression
Neuropathy
Fibromyalgia
Anxiety
Insomnia
Mode of Action
Increases the effect of serotonin and norepinephrine in the CNS
Side Effects
Sedation
Orthostatic hypotension
Anticholinergic effects:
Urinary retention
Constipation
Dry mouth
Photophobia
Tachycardia
Sweating
Seizures
Arrhythmias
Memory Aids
Rhyme
: Can’t see, can’t pee, can’t spit, and can’t poop
Cool Chicken Hint
: Amy tripping over a tricycle in the desert (dry effects)
Patient Teaching Points
Change positions slowly (due to orthostatic hypotension)
Chewing gum or sucking on hard candy for dry mouth
Increase fluid and fiber intake to prevent constipation
Quiz Questions
Question
: Diarrhea is a key side effect of amitriptyline. True or false?
Answer
: False – Anticholinergic effects include constipation
Question
: Bradycardia is a key side effect of imipramine. True or false?
Answer
: False – Anticholinergic effects include tachycardia
Question
: You should teach your patient to change positions slowly due to the risk for
blank
when taking a tricyclic antidepressant.
Answer
: Orthostatic hypotension
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Full transcript