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Gland Structure and Classification

Oct 2, 2025

Overview

This lecture covers the structure, types, and classification methods of glands, focusing on their composition, secretion mechanisms, and examples.

General Structure and Function of Glands

  • Glands are organs or cells that produce and secrete substances for body use.
  • Most glands consist of epithelial tissue.
  • Glandular secretions include mucin, hormones, electrolytes, enzymes, and waste products.

Classification: Endocrine vs. Exocrine Glands

  • Endocrine glands secrete hormones directly into the blood or interstitial fluid.
  • Examples of endocrine glands: adrenal, thyroid, pituitary.
  • Exocrine glands secrete products into ducts or onto external surfaces, not into the blood.
  • Exocrine glands may be unicellular (no ducts) or multicellular (with ducts).

Unicellular and Multicellular Exocrine Glands

  • Unicellular exocrine glands (e.g., goblet cells) secrete mucin and lack ducts.
  • Goblet cells create mucus layers over tissues like the trachea.
  • Multicellular exocrine glands have duct systems and can be classified by form or secretion method.

Classification by Gland Form

  • Simple glands have a single duct; compound glands have branching ducts.
  • Secretory portions can be tubular (uniform diameter) or acinar/alveolar (sac-shaped).
  • Examples: simple straight tubular, coiled tubular, simple branched tubular (all one duct), simple acinar, simple branched acinar.
  • Compound glands include compound tubular, compound acinar, and compound tubuloacinar (mixed tubular and acinar).

Classification by Secretion Method

  • Merocrine glands release products via exocytosis without cell damage; example: salivary glands.
  • Apocrine glands pinch off cell portions to release products; examples: mammary and some sweat glands.
  • Holocrine glands release products by cell rupture and are replaced by new cells; examples: certain skin and eyelid glands.

Key Terms & Definitions

  • Gland — Organ or cell that produces and releases substances.
  • Epithelial tissue — Tissue type making up most glands.
  • Endocrine gland — Gland releasing hormones into blood or interstitial fluid.
  • Exocrine gland — Gland releasing products into ducts or onto surfaces.
  • Unicellular gland — Single-cell gland, no ducts (e.g., goblet cell).
  • Multicellular gland — Gland with multiple cells and duct(s).
  • Simple gland — One duct.
  • Compound gland — Branching ducts.
  • Tubular — Uniform, tube-like secretory portion.
  • Acinar/Alveolar — Sac-shaped secretory portion.
  • Merocrine — Secretion via exocytosis.
  • Apocrine — Secretion via pinched-off cell portions.
  • Holocrine — Secretion via complete cell rupture.

Action Items / Next Steps

  • Review the structure and functions of individual glands in future lectures or assigned readings.