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Exploring Non-Mendelian Genetics Principles Lecture 1

Oct 28, 2024

D18 - Non-Mendelian Genetics Pt 1

Overview

  • Introduction to Non-Mendelian Genetics.
  • Focus on genetic inheritance patterns that do not follow Mendel's principles.

Key Concepts

1. Non-Mendelian Inheritance

  • Definition: Genetic inheritance patterns that do not adhere to Mendel's laws.
  • Examples include:
    • Incomplete Dominance: A situation where the phenotype of heterozygotes is intermediate between the phenotypes of individuals homozygous for either allele.
    • Codominance: Both alleles are fully expressed in the heterozygous condition.
    • Multiple Alleles: More than two alleles exist for a particular gene.
    • Polygenic Inheritance: Traits that are controlled by more than one gene.

2. Incomplete Dominance

  • Example: Snapdragons, where red and white flowers produce pink offspring.
  • Significance: Shows blending of traits.

3. Codominance

  • Example: AB blood type in humans where both A and B antigens are expressed.
  • Significance: Demonstrates simultaneous expression of both alleles.

4. Multiple Alleles

  • Example: ABO blood group system.
  • Explanation: Existence of more than two allele forms within a population.

5. Polygenic Inheritance

  • Traits influenced by multiple genes, resulting in continuous variation.
  • Example: Human skin color, height.

Implications of Non-Mendelian Inheritance

  • Greater genetic diversity within populations.
  • Complex patterns of inheritance that contribute to phenotypic variation.
  • Impact on genetic counseling and understanding hereditary diseases.

Conclusion

  • Non-Mendelian genetics broadens the understanding of inheritance beyond simple dominant-recessive relationships.
  • Essential for understanding complex genetic traits and variations.