Thyroid Gland Anatomy and Relations

Jul 28, 2025

Overview

This lecture covered the external anatomy, parts, and important surgical relations of the thyroid gland, with emphasis on surface anatomy and clinical relevance.

Location and Surface Anatomy

  • The thyroid gland is shield-shaped and lies low in the front of the neck, below and lateral to the thyroid cartilage.
  • It is not at the laryngeal prominence (Adam’s apple) but below it; vertebral level C5 to T1.
  • Weighs 20–25 grams, depending on body weight and iodine intake.
  • Highly vascular, brown, firm, and secretes thyroxine (regulates metabolism) and calcitonin (lowers blood calcium).

Parts and Structure

  • The gland is H-shaped: two lobes connected by a central isthmus.
  • Isthmus lies in front of the 2nd-4th tracheal rings; lobes lie on either side of larynx and trachea.
  • Each lobe extends from the oblique line of thyroid cartilage to the sixth tracheal ring.
  • Pyramidal lobe (present in ~30%): an upward extension from the isthmus, sometimes connected to the hyoid bone by the levator glandulae thyroideae (fibrous band).
  • The pyramidal lobe is a remnant of the thyroglossal duct.

Capsule and Fascia

  • Covered by two capsules: true capsule (dense fibrous, adherent) and false capsule (derived from pretracheal fascia, easily separated).
  • Venous plexus lies inside true capsule (contrast: in prostate, it's outside true capsule).
  • Ligament of Berry: dense posterior-medial condensation attaching gland to cricoid cartilage and first tracheal ring; key fixation and surgical landmark.

Relations and Surfaces

  • Apex of lobes reaches oblique line of thyroid cartilage, limited by sternothyroid muscle.
  • Base of gland at 5th/6th tracheal ring, related to inferior thyroid artery and recurrent laryngeal nerve.
  • Lateral (superficial) surface covered by sternothyroid, sternohyoid, and superior belly of omohyoid muscles.
  • Medial surface contacts trachea, esophagus, inferior constrictor, cricothyroid muscles, cricoid and thyroid cartilage, and is near external and recurrent laryngeal nerves.
  • Posterolateral surface related to parathyroid gland and carotid sheath.
  • Anterior border related to superior thyroid artery; posterior border to arterial anastomoses between superior and inferior thyroid arteries.

Isthmus

  • Connects the lobes, has anterior and posterior surfaces, superior and inferior borders.
  • Anteriorly related to sternohyoid, sternothyroid muscles, and anterior jugular vein.
  • Posterior surface related to 2nd, 3rd, 4th tracheal rings.
  • Superior border: arterial anastomosis (superior thyroid arteries); inferior border: exit for inferior thyroid vein, possible entry of thyroid ima artery.

Clinical and Surgical Relevance

  • Thyroid moves with swallowing due to connection with laryngeal cartilages and hyoid bone via pretracheal fascia.
  • Ligament of Berry is crucial in surgery due to proximity to recurrent laryngeal nerve and inferior thyroid artery branch.

Key Terms & Definitions

  • Isthmus — central part connecting right and left thyroid lobes.
  • Pyramidal lobe — an upward extension of thyroid tissue, remnant of the thyroglossal duct.
  • True capsule — dense, adherent fibrous covering of the gland.
  • False capsule — loose covering from pretracheal fascia, easily separated.
  • Ligament of Berry — dense band fixing thyroid to cricoid cartilage, key in gland fixation.
  • Thyroxine — hormone increasing cell metabolism.
  • Calcitonin — hormone lowering blood calcium.

Action Items / Next Steps

  • Review diagrams of thyroid anatomy and relations.
  • Practice palpation of the thyroid gland below the Adam’s apple.
  • Know the surgical relevance of ligament of Berry and surface anatomy for exams.