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Prioritizing Differential Diagnoses in Assessment
Sep 3, 2024
Assessment of Reasoning Tool (ART)
Purpose
To assess a learner's ability to construct a prioritized differential diagnosis.
Focus on probability ranking based on problem representation.
Steps in Constructing a Prioritized Differential Diagnosis
Select Leading Hypothesis
Choose the most probable diagnosis based on available evidence.
Consider Can't-Miss Hypotheses
Identify serious or emergent diseases that must not be overlooked.
Consider Less Likely and Unlikely Hypotheses
Evaluate alternative diagnoses that are less probable.
Problem Representation
A concise synthesis of the clinical problem.
Addresses three key questions:
Who is the patient?
What is the clinical syndrome?
What is the time course?
Compare potential diseases (illness scripts) with the problem representation.
Higher match increases the likelihood of a diagnosis explaining the patient's presentation.
Evidence in Diagnosis Ranking
Accompany diagnoses with clinical evidence that supports or refutes each possibility.
Include consideration for can't-miss diagnoses.
Evaluating Learner's Reasoning
Analyze spoken or written assessments for main problems.
Case Study Example
High Performer Example
Patient:
Julio Martinez, 27-year-old woman, hyperthyroidism, two days of nausea, vomiting, diarrhea, left upper quadrant pain.
Most Likely:
Viral gastroenteritis (nausea, vomiting, diarrhea, acuity).
Less Likely:
Food poisoning (absence of illness in dining companions).
Unlikely:
Appendicitis (location and diarrhea don't match).
Can't-Miss:
Ectopic pregnancy (considered in young women with abdominal pain).
Note:
Clear probability tiers and evidence for/against each condition.
Low Performer Example
Lists diagnoses: appendicitis, ectopic pregnancy, food poisoning.
Acknowledges emergent conditions but lacks probability delineation.
No evidence for or against diagnoses.
Summary
A prioritized differential diagnosis ranks diseases based on their match to the problem representation.
Must include can't-miss diagnoses.
Should articulate supporting and refuting evidence for each diagnosis.
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Full transcript