Question 1
How do high levels of NADPH regulate G6PD?
Question 2
Which enzyme catalyzes the conversion of glucose 6-phosphate to 6-phosphoglucono-δ-lactone in the PPP?
Question 3
Which enzyme regenerates reduced glutathione using NADPH?
Question 4
When the body needs both ribose 5-phosphate and NADPH, which phase of the PPP is utilized?
Question 5
What metabolic need is addressed by utilizing both the oxidative phase of PPP and glycolysis?
Question 6
What is the main role of NADPH produced in the PPP?
Question 7
What stimulates glucose 6-phosphate dehydrogenase (G6PD) in the pentose phosphate pathway?
Question 8
Which enzyme in the PPP specifically converts superoxide anion to hydrogen peroxide?
Question 9
Which intermediates can ribose 5-phosphate be converted back to in order to regenerate glucose?
Question 10
Which enzymes are involved in the conversion of glycolytic intermediates into ribose 5-phosphate in the non-oxidative phase?
Question 11
In which scenario is both the oxidative phase of PPP and gluconeogenesis active?
Question 12
What is a possible consequence of G6PD deficiency?
Question 13
Which phase of the PPP is active when the need is only for ribose 5-phosphate?
Question 14
In the scenario where both ribose 5-phosphate and NADPH are needed, what is ribose 5-phosphate mainly used for?
Question 15
NADPH is crucial in the detoxification of reactive oxygen species through its role in reducing which molecule?