Back to notes
Explain the role of antigen-presenting cells (APCs) in T cell activation.
Press to flip
APCs display antigens to Helper T cells to initiate their activation and subsequent immune response.
Why are T cells important in adaptive immunity?
T cells are crucial for identifying and destroying infected host cells, providing targeted immunity.
What is the primary role of cell mediated immunity?
Targeting pathogens that hide inside the body's own cells, such as viruses and some bacteria.
How do Helper T cells ensure effective targeting of pathogens?
By coordinating both humoral and cell-mediated immune responses, targeting pathogens in body fluids and inside cells.
How do Cytotoxic T cells initiate cell death in infected cells?
Cytotoxic T cells use lysis to puncture infected cell membranes, causing cell contents to spill out and lead to cell death.
What is the maturation location for T lymphocytes?
T cells mature in the thymus.
Describe the function of Cytotoxic T cells (CD8+ T cells).
Cytotoxic T cells target and destroy infected cells by puncturing cell membranes and inducing cell death.
What happens to B cells after they are activated by Helper T cells?
Activated B cells divide into plasma cells, which produce antibodies.
What is the significance of co-stimulation in T cell activation?
Co-stimulation ensures that T cells receive additional activating signals from APCs, enhancing the immune response.
How does cell mediated immunity differ from humoral immunity?
Cell mediated immunity targets pathogens inside body cells with T cells, while humoral immunity targets pathogens in body fluids with B cells.
What role do Helper T cells (CD4+ T cells) play in the immune system?
Helper T cells act as 'generals' in the immune system, coordinating immune responses.
What do dendritic cells do in the context of T cell activation?
Dendritic cells act as antigen-presenting cells to help activate Helper T cells by displaying specific antigens.
During B cell activation in humoral immunity, how do Helper T cells contribute?
Helper T cells secrete chemicals to activate B cells after B cells present antigens to them.
What differentiates the action of Helper T cells and Cytotoxic T cells?
Helper T cells coordinate immune responses, while Cytotoxic T cells directly attack and destroy infected cells.
What is the two-step process for activating Helper T cells?
1. Dendritic cells or other APCs present antigens to Helper T cells, activating them. 2. Co-stimulation occurs through interactions with APCs developing new surface receptors.
Previous
Next