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Understanding Tumor Classification and Staging

Apr 29, 2025

Tumor Classification Lecture Notes

Key Topics

  • Tissue Type
  • Grading of Cancer
  • Staging of Cancer

Tissue Type of Cancer

Cancer types are categorized by the type of tissue where they originate. The five main types include:

  1. Carcinomas

    • Make up 80-90% of cancers.
    • Originate in epithelial tissue (lines body surfaces, cavities, glands, and organs).
    • Subtypes:
      • Adenocarcinomas: Originate in organs or glands that secrete substances (e.g., mucus).
      • Squamous Cell Carcinoma: Originate in the squamous epithelium.
  2. Sarcomas

    • Originate in supportive or connective tissues.
    • Examples: Osteosarcoma (bone cancer), Chondrosarcoma (cartilage cancer).
  3. Leukemia

    • Originates in the bone marrow.
  4. Myeloma

    • Originates in plasma cells in the bone marrow.
  5. Lymphoma

    • Originates in lymphatic glands, nodes, or organs (e.g., thymus, spleen).

Grading of Cancer

  • Comparison of cancer to the tissue of origin is crucial.
  • Grading scale: 1 to 4.
    • Grade 1: Well differentiated, resembles tissue of origin, usually grows slowly.
    • Grade 4: Poorly differentiated, does not resemble tissue of origin, grows and spreads rapidly.

Staging of Cancer

Staging is done using the TNM system:

  1. T (Tumor)

    • Indicates size and extent of the tumor.
    • T1 (small tumor) to T4 (large tumor).
  2. N (Node)

    • Refers to the number of regional lymph nodes involved.
    • N0 (no lymph nodes affected) to N3 (multiple lymph nodes affected).
  3. M (Metastasis)

    • Indicates if cancer has spread to other parts of the body.
    • M0 (no metastasis) or M1 (metastasis present).

Conclusion

Understanding tumor classification is crucial for diagnosing and planning treatment strategies. The next video will cover nursing care and patient education concerning cancer treatment complications.