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Protein Intake for Muscle Growth

Jul 16, 2025

Overview

This lecture addresses optimal protein intake for muscle building post-resistance training, discussing timing, amount, and the concept of the "anabolic window."

Recommended Protein Intake Post-Resistance Training

  • An effective dose for maximizing muscle protein synthesis is 0.4–0.6 g/kg (0.2–0.25 g/lb) body weight per meal.
  • Typical post-training meals should contain 30–50 g of protein but doses above this are rarely studied.
  • Total daily intake should be approximately 1.6–2.2 g/kg (0.7–1 g/lb) body weight for optimal muscle gain.

Protein Timing and the Anabolic Window

  • Early research suggested a narrow 30–60 minute post-exercise "anabolic window" for protein intake.
  • This hypothesis was based on fasted subjects but is less relevant if a pre-exercise meal was consumed.
  • The anabolic/anti-catabolic effect of a meal can last 3–6 hours, depending on meal size.
  • Meta-analyses show that as long as total daily protein meets recommended levels, timing relative to training is not crucial for most people.

Protein Distribution and Practical Considerations

  • Even if protein intake is uneven through the day (e.g., heavier at dinner), there is no major negative impact on muscle or health for general populations.
  • Studies comparing protein intake immediately pre- vs post-exercise show no significant difference in muscle or strength gains.
  • Nutrients take 1–2 hours to peak in circulation, meaning pre-exercise meals contribute to post-exercise recovery.
  • Muscle protein synthesis remains elevated for up to 24–72 hours after resistance training.

Hierarchy of Protein Importance

  • Total daily protein intake is most important; timing is secondary.
  • The "anabolic window" is more flexible than previously thought, spanning hours to days.
  • Protein timing becomes more critical only for elite athletes or those with highly specific physique goals.

Key Terms & Definitions

  • Muscle Protein Synthesis (MPS) — The process by which the body builds new muscle proteins after exercise.
  • Anabolic Window — The theorized short time after exercise when nutrient intake is thought to maximize muscle growth.
  • Meta-analysis — A study that combines results from multiple studies to draw broader conclusions.

Action Items / Next Steps

  • Calculate your protein needs: aim for 0.7–1 g per lb body weight daily.
  • Focus on total daily protein rather than obsessing over timing post-exercise.
  • Distribute protein across meals as convenient; do not stress over exact post-workout intake timing.