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Osmotic Pressure Overview

Aug 11, 2025

Overview

This lecture explains the concept of osmotic pressure in solutions, its everyday applications, and methods for calculating osmotic pressure, particularly for non-electrolyte and electrolyte solutions.

Osmotic Pressure: Definition and Concepts

  • Osmotic pressure is the hydrostatic pressure created by the osmosis process.
  • Osmosis is the movement of solvent from a hypotonic (dilute) solution to a hypertonic (concentrated) solution through a semipermeable membrane.
  • In osmosis, the solvent always moves from the lower solute concentration (hypotonic) to a higher solute concentration (hypertonic).
  • Applications include salted egg production, making candied fruit, IV infusions for patients, and dialysis for kidney failure.

Applications of Osmotic Pressure

  • IV fluids use osmotic pressure principles to match body fluid concentrations.
  • Dialysis involves transferring small molecules like urea through a semipermeable membrane by osmotic pressure.
  • Reverse osmosis is used in desalination (removing salt from seawater).

Calculating Osmotic Pressure

  • General formula: PV = nRT (gas law applied to solutions).
  • For non-electrolyte solutions: Ï€ = MRT (where Ï€ = osmotic pressure, M = molarity, R = gas constant, T = temperature in Kelvin).
  • For electrolyte solutions, account for ionization: Ï€ = iMRT (i = van 't Hoff factor).

Example Calculations

  • Glucose infusion: Use Ï€ = MRT, substituting known values for glucose (a non-electrolyte) to calculate osmotic pressure.
  • Isotonic NaCl solution: Find the required mass of NaCl to match blood's osmotic pressure (7.7 atm at 37°C), using the Molar Mass of NaCl and Ï€ = iMRT.

Key Terms & Definitions

  • Osmotic Pressure — Pressure needed to prevent the flow of solvent through a semipermeable membrane from a dilute to a concentrated solution.
  • Semipermeable Membrane — Membrane allowing only certain molecules (typically solvent) to pass through.
  • Hypotonic Solution — Solution with a lower solute concentration than another solution.
  • Hypertonic Solution — Solution with a higher solute concentration than another solution.
  • Isotonic Solution — Solutions with equal osmotic pressure.
  • Molarity (M) — Moles of solute per liter of solution.
  • Gas Constant (R) — 0.082 L atm/mol K.
  • Van 't Hoff Factor (i) — Number of particles a compound forms in solution.

Action Items / Next Steps

  • Read about hypertonic, isotonic, and hypotonic solutions for deeper understanding.
  • Complete the practice problems in your notebook and submit them after the chapter is finished.