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Prokaryotes vs Eukaryotes Overview

May 14, 2025

Prokaryotes vs Eukaryotes: Key Differences

Overview

  • Two Groups of Organisms: All living organisms are categorized as either prokaryotes or eukaryotes, distinguished by cellular structure.
    • Prokaryotes: Unicellular, no nucleus or membrane-bound organelles, includes bacteria and archaea, smaller and simpler.
    • Eukaryotes: Often multicellular, has a nucleus and membrane-bound organelles, includes animals, plants, fungi, algae, protozoans, larger and more complex.

Comparing Prokaryotes and Eukaryotes

  • Evolution: Eukaryotes are believed to have evolved from prokaryotes about 2.7 billion years ago through endosymbiosis.
  • Endosymbiosis: Led to development of mitochondria and other organelles.
  • New Research: Suggests prokaryotic bacteria may perform endocytosis, challenging previous understanding.

Key Differences

  • Nucleus:
    • Prokaryotes: Absent, DNA is bundled in the nucleoid, not membrane-bound.
    • Eukaryotes: Present, stores genetic information.
  • Organelles:
    • Prokaryotes: No membrane-bound organelles.
    • Eukaryotes: Contains various membrane-bound organelles.
  • DNA Structure:
    • Prokaryotes: Generally circular, but can also be linear in some cases.
    • Eukaryotes: Linear DNA.
  • Cell Structure:
    • Prokaryotes: Unicellular.
    • Eukaryotes: Mostly multicellular, some unicellular.

Similarities

  • Shared features of both cell types include DNA, plasma membrane, cytoplasm, and ribosomes.

Transcription and Translation

  • Prokaryotes: Transcription and translation are coupled; translation begins during mRNA synthesis.
  • Eukaryotes: Transcription occurs in the nucleus, mRNA exits, and translation occurs in the cytoplasm.

Prokaryotes

  • **Features: **
    • Nucleoid: Contains DNA.
    • Ribosome: Protein synthesis.
    • Cell Wall: Structure and protection.
    • Cell Membrane: Separates cell from environment.
    • Capsule: Protection and attachment.
    • Pili and Flagella: Movement and DNA transfer.
  • Examples: Bacteria, archaea.
  • Organelles: No nucleus or mitochondria.

Eukaryotes

  • Features:
    • Nucleus and Nucleolus: Stores and produces genetic material.
    • Plasma Membrane and Cytoskeleton: Encloses cell and maintains shape.
    • Cell Wall: Present in some eukaryotes like plants.
    • Ribosomes and Mitochondria: Protein synthesis and energy production.
    • Cytoplasm and Cytosol: Fill the cell and contain organelles.
    • Endoplasmic Reticulum, Vesicles, and Vacuoles: Organelles for protein maturation, transport, and storage.
    • Other Organelles: Golgi apparatus, chloroplasts, lysosomes (in many eukaryotes).
  • Examples: Animals, plants, fungi, algae, protozoans.