Comprehensive Guide to Nail Anatomy

May 6, 2025

Nail Anatomy

Overview

  • The nail unit includes:
    • Nail plate
    • Surrounding soft tissues
    • Vasculature and innervation related to the distal phalanx
  • Key structures:
    • Laminated keratinized nail plate
    • Nail matrix and bed
    • Proximal and lateral nail folds
    • Cuticle (eponychium)
    • Hyponychium at the free edge

Nail Plate

  • A modified form of the stratum corneum
  • Provides a laminated keratinized structure
  • Overlies the nail bed and matrix
  • Examined using silver stains, ultrasound, optical coherence tomography, and electron microscopy
  • Typically trilaminar but can appear bilaminar

Nail Folds

Lateral Nail Folds

  • Provide cushioned cutaneous lateral margins
  • More prominent in toes than fingers
  • Important for nail adherence to the nail bed
  • Issues like onycholysis or ingrown nails can occur if fold size is not compatible with the nail plate size

Proximal Nail Fold (Posterior Nail Fold)

  • Originates around week 14 of embryogenesis
  • Adherent to the dorsal aspect of the nail plate
  • Protects the nail matrix from damage and UV light

Cuticle (Eponychium)

  • Epidermal layer extending from the proximal nail fold
  • Adheres to the dorsal nail plate
  • Loss can indicate chronic paronychia
  • Regrowth signifies resolution of inflammation

Nail Matrix and Lunula (Nail Root)

  • Divided into matrix (15-25%) and nail bed (75-85%)
  • Lunula is the visible part of the distal matrix in some digits
  • Important for surgical landmarks and nail excision

Nail Bed (Ventral Matrix, Sterile Matrix)

  • Extends from the lunula to the hyponychium
  • Features longitudinal epidermal ridges
  • Small vessels aligned in the same axis

Onychodermal Band

  • Distal nail bed margin with a contrasting hue
  • Acts as the first barrier to penetration under the nail plate
  • Its state can indicate disease or trauma

Vascular and Nervous System

Arterial Supply

  • Radial and ulnar arteries supply the digits
  • Forms deep and superficial palmar arcades
  • Four arteries per digit with dorsal and palmar digital arteries

Venous Drainage

  • Deep and superficial venous systems
  • Prominent branching network, especially dorsally

Effects of Altered Vascular Supply

  • Impaired supply affects nail unit health
  • Linked to conditions like onycholysis and congenital onychodysplasia

Nail Fold Vessels

  • Capillary network can be viewed with a dermatoscope
  • The venous arm is more dilated than the arterial

Glomus Bodies

  • Small cluster of cavernous blood vessels
  • Part of arteriovenous anastomosis

Nerve Supply

  • Innervation by dorsal branches of paired digital nerves
  • Important for anesthesia in nail surgery

Distal Phalanx

  • Related to nail unit embryogenesis and lifelong changes
  • Nail plate dystrophies linked to phalanx structure

Conclusion

  • Understanding the intersection of anatomy, physiology, and disease aids in analyzing nail pathologies
  • Essential for planning surgery and therapeutic strategies.