Lecture on Donepezil and Rivastigmine

Overview

• Donepezil and Rivastigmine are cholinesterase inhibitors used to treat Alzheimer's disease.
• Use mnemonic aids to remember key facts about these drugs.

Mnemonic Imagery

• Pixar Island as the theme for memory anchors:
  • Donuts symbolize Donepezil (Donuts = Donepezil).
  • River symbolizes Rivastigmine (River = Rivastigmine).

Mechanism of Action

• Both drugs increase acetylcholine levels in the body.
  • Symbolized by fridge stocked with cola bottles (Cola = Choline).

Alzheimer's Disease Association

• Old confused alchemist at donut stand symbolizes Alzheimer's disease (Alchemist = Alzheimer).
  • Alzheimer's disease affects elderly people, leading to dementia and confusion.
  • Both drugs help by increasing acetylcholine, which can improve memory.

Key Points About the Drugs

• Donepezil and Rivastigmine:
  • Treat Alzheimer's disease.
  • Cannot cure or prevent the disease.
  • Slow symptomatic progression and improve cognition.

Recap

• Mnemonics: Donuts for Donepezil and River for Rivastigmine.
• Mechanism: Increase acetylcholine levels.
• Improves cognitive function in Alzheimer's patients but not a cure or preventive.

Closing

• Further resources include videos, fact lists, and interactive review images available on the channel.