Question 1
Which syndrome is characterized by an abnormal buildup of blasts (<20%) in the bone marrow and can progress to AML?
Question 2
What cell markers are commonly seen in T-cell acute lymphoblastic leukemia (T-ALL)?
Question 3
What cellular marker is used to identify lymphoid blasts in acute lymphoblastic leukemia (ALL)?
Question 4
Which chromosomal translocation is associated with a poor prognosis in adult B-ALL?
Question 5
What is a major risk associated with acute promyelocytic leukemia (APL) due to the presence of Auer rods?
Question 6
Which leukemia subtype is associated with gum infiltration and lacks myeloperoxidase?
Question 7
Which enzyme is found in myeloid blasts and can also crystallize into Auer rods?
Question 8
What specific chromosomal translocation is associated with a good prognosis in B-ALL, particularly common in children?
Question 9
What percentage of blasts in the bone marrow is indicative of acute leukemia?
Question 10
In T-ALL, what differentiates this leukemia from B-ALL regarding the presentation site in teenagers?
Question 11
What additional treatment is used for B-ALL to address potential CNS and testes infiltration?
Question 12
What common markers are associated with B-cell acute lymphoblastic leukemia (B-ALL)?
Question 13
Which cell lineages can hematopoietic stem cells differentiate into?
Question 14
Which subtype of AML is particularly associated with Down syndrome before age 5?
Question 15
Which subtype of acute myeloid leukemia (AML) is associated with the t(15;17) translocation?