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Homeostasis and Feedback

Aug 21, 2025

Overview

The lecture introduces the receptor-control center-effector circuit diagram, illustrating how negative feedback mechanisms maintain homeostasis, particularly body temperature, with both physiological and real-world (HVAC) examples.

The Receptor-Control Center-Effector Circuit

  • The circuit consists of a receptor (sensor), control center (decision-maker), and effector (responder).
  • The receptor gathers information about internal or external conditions and sends it to the control center.
  • The control center processes input, decides on a response, and signals the effector.
  • The effector takes action to adjust the condition back toward the desired range.

Homeostasis and Body Temperature

  • Homeostasis refers to maintaining ideal internal conditions for body function, such as temperature.
  • Normal body temperature averages around 98.6Β°F but varies by individual and throughout the day.
  • Each person has a temperature setpoint, with normal fluctuations around that point.

Negative Feedback Mechanism: HVAC Analogy

  • In an HVAC system, room temperature is regulated within a set window (e.g., 68–69Β°F) by negative feedback.
  • The thermometer (receptor) senses temperature and informs the thermostat (control center).
  • If the temperature rises, the air conditioner (effector) cools the room; if it falls, the furnace (effector) heats the room.
  • The system works to counteract deviations from the setpoint, maintaining homeostasis.

Body Temperature Regulation Example

  • Body thermo receptors (receptors) detect temperature changes and send signals to the hypothalamus (control center).
  • If body temperature rises, sweat glands and vasodilation (effectors) cool the body.
  • If body temperature falls, shivering and blood vessel constriction (effectors) warm the body.
  • These are examples of negative feedback correcting deviations from the temperature setpoint.

Key Terms & Definitions

  • Receptor β€” A sensor detecting changes in the environment or body.
  • Control Center β€” Receives receptor input, processes it, and decides on a response.
  • Effector β€” Carries out the action to restore homeostasis.
  • Homeostasis β€” Maintenance of stable internal conditions within a physiological range.
  • Negative Feedback β€” A process that counteracts changes, returning conditions to a setpoint.

Action Items / Next Steps

  • Review the circuit diagram for receptor-control center-effector.
  • Be prepared to see this model applied to other physiological systems in future lectures.