Overview of Swallowing Mechanisms

Aug 26, 2024

Lecture on Deglutition (Swallowing)

Importance of Deglutition

  • Essential for nutrient absorption from food (e.g., pizza).
  • Involves moving food from the oral cavity to the stomach.

Phases of Deglutition

  • Oral Phase
  • Pharyngeal Phase
  • Esophageal Phase

Oral Phase

  • Anatomy & Boundaries of the Oral Cavity

    • Anterior: Oral vestibule.
    • Posterior: Palatoglossal arch.
  • Depression of the Mandible

    • Muscles involved: Lateral pterygoid, digastric (anterior belly), mylohyoid, geniohyoid.
    • Innervation: Cranial nerve V (Trigeminal nerve, V3 mandibular division), Cervical plexus (C1 ramus).
  • Elevation of the Mandible

    • Muscles involved: Masseter, temporalis, medial pterygoid.
    • Innervation: Cranial nerve V (Trigeminal nerve, V3 mandibular division).
  • Mechanical Digestion

    • Teeth functions: Incisors (cutting), canines (tearing), molars (grinding).
  • Salivation

    • Types: Intrinsic (10%), Extrinsic (90% - parotid, submandibular, sublingual).
    • Functions: Lubricate food, begin chemical digestion (salivary amylase for carbohydrates, lingual lipase for fats).
  • Bolus Formation

    • Tongue muscles: Intrinsic (form central trough), Extrinsic (elevate tongue).
    • Innervation: Cranial nerve XII (Hypoglossal nerve).

Pharyngeal Phase

  • Sensory Activation

    • Initiated by bolus touching the palatoglossal arch.
    • Innervation: Cranial nerve IX (Glossopharyngeal nerve).
  • Preventing Nasopharyngeal Entry

    • Elevation of uvula and soft palate (levator veli palatini, tensor veli palatini).
    • Innervation: Cranial nerve X (Vagus nerve), Cranial nerve V (Trigeminal nerve, V3).
  • Preventing Laryngeal Entry

    • Approximation of vocal cords (lateral cricoarytenoids, arytenoid muscles).
    • Epiglottis retroversion.
  • Ensuring Pharyngeal Passage

    • Muscles: Palatoglossus, palatopharyngeus (approximate walls).
    • Outer longitudinal muscles: Styloglossus, salpingopharyngeus, palatopharyngeus (elevate pharynx and larynx).
    • Inner circular muscles: Pharyngeal constrictors (superior, middle, inferior).
  • Upper Esophageal Sphincter (UES)

    • Muscle: Cricopharyngeus (part of inferior pharyngeal constrictor).
    • Function: Relaxation allows bolus entry into the esophagus.

Esophageal Phase

  • Peristalsis

    • Primary: Continuation of pharyngeal peristalsis.
    • Innervation: Cranial nerve X (Vagus nerve).
  • Lower Esophageal Sphincter (LES) Function

    • Allows bolus entry into the stomach.
  • Secondary Peristalsis

    • Triggered by bolus stuck in the esophagus.
    • Local reflex via the myenteric plexus.

Conclusion

  • Deglutition is a complex, coordinated process involving multiple phases and nerve innervations to ensure safe and efficient swallowing.
  • Critical for nutrient absorption and preventing aspiration.