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Introduction to Genetics Concepts

May 6, 2025

Introduction to Genetics

Overview

  • Lecture by Miss Angler for grade 8 to 12 biology.
  • Video is an introduction to genetics.
  • More detailed content available in Grade 12 playlist covering monohybrid and dihybrid crosses, sex-linked disorders.

Basics of Genetics

Chromatin Network

  • Found inside the nucleus of cells.
  • Condenses into chromosomes during cell division (mitosis and meiosis).
  • Chromosomes:
    • Collection of DNA.
    • Humans have 46 chromosomes.
    • DNA is condensed to form chromosomes.

DNA and Genes

  • DNA: Code of life, codes for all proteins in the body.
  • Genes: Sections of DNA coding for specific characteristics (e.g., height, hair color, blood group).
  • Characteristics expressed physically by genes.

Gene vs Allele

  • Gene: Characteristic (e.g., eye color, height, blood group).
  • Allele: Variation of a gene (e.g., blue or brown eye color).
  • Homologous chromosomes carry alleles for the same gene.
    • Example: Blue eye allele on one chromosome, green on another.

Inheritance of Characteristics

Chromosomes and Inheritance

  • Humans have homologous pairs of chromosomes.
    • One from mother (maternal), one from father (paternal).
  • Each gene has two alleles (one maternal, one paternal).
  • Alleles passed individually during reproduction (meiosis).

Alleles in Action

  • Alleles located at specific loci on chromosomes.
  • Example given: Eye color alleles on homologous chromosomes.

Dominant and Recessive Alleles

  • Dominant alleles: Use capital letters (e.g., B).
  • Recessive alleles: Use lowercase letters (e.g., b).
  • Allele combinations affect phenotype (physical appearance):
    • BB (homozygous dominant): Purple flower.
    • Bb (heterozygous): Purple flower (dominant masks recessive).
    • bb (homozygous recessive): White flower.

Terminology Recap

  • Chromatin Network: Structure containing DNA.
  • Chromosomes: Carry DNA, visible during cell division.
  • Genes: Code for specific traits.
  • Alleles: Variations of genes.
  • Paternal and Maternal Chromosomes: Inherited from parents, separate during meiosis.
  • Dominant Alleles: Expressed even if only one copy is present.
  • Recessive Alleles: Require two copies to be expressed.
  • Homozygous: Two identical alleles (dominant or recessive).
  • Heterozygous: One dominant and one recessive allele.

Conclusion

  • Regular content updates every Tuesday and Thursday.