Overview
This lecture reviews essential lab values for nursing, explaining their meanings, normal ranges, clinical significance, and highlighting high-yield facts for NCLEX and nursing exams.
Basic Metabolic Panel (BMP) & Electrolytes
- BMP screens sodium (Na: 135-145), potassium (K: 3.5-5.0), chloride, CO₂, bicarb (HCO₃), BUN (10-20), creatinine (<1.3), and glucose (70-115).
- Sodium swells the body; low causes mental status changes, seizures, high causes edema, red skin.
- Potassium "pumps" muscles, especially the heart; high (K>5.0) = peaked T-waves, low (K<3.5) = flat T-waves, U-waves.
- Never IV push potassium; always use infusion pump, max 10-20mEq/hr.
- Treat high K: 1st IV calcium gluconate if dysrhythmias, 2nd insulin+glucose, 3rd Kayexalate/dialysis.
Calcium & Magnesium
- Calcium (9.0–10.5): contracts muscles; low = Trousseau’s, Chvostek’s signs, diarrhea; high = kidney stones, constipation.
- Magnesium (1.3–2.1): mellows muscles; low = hyperreflexia, torsades; high = decreased reflexes.
Complete Blood Count (CBC)
- Hemoglobin (Hgb: 12-18): carries Oâ‚‚; <7 = critical transfusion trigger.
- Hematocrit (Hct: 36-54): ratio of RBC:plasma; high = dehydration, low = fluid overload/bleeding.
- White Blood Cells (WBC: 5,000-10,000): high = infection, low = neutropenia (watch for fever).
- Platelets (Plt: 150,000-400,000): low = bleed risk, <50,000 = very risky.
Coagulation Studies
- PTT (Heparin): 46-70 seconds therapeutic; >70 = hold drug, prep antidote (protamine sulfate).
- INR (Warfarin): 2-3 therapeutic; >3 = hold, check for bleeding, prep vitamin K.
- Platelets <50,000 = hold antiplatelets/anticoagulants.
Cardiac, Renal, Liver Labs
- Troponin >0.5 = acute MI.
- BNP >100 indicates CHF.
- Creatinine >1.3 signals kidney injury; BUN >20 = dehydration.
- Albumin <3.5, elevated ammonia, bilirubin, ALT/AST in liver failure; monitor mental status for encephalopathy.
Acid-Base, Diabetes, & Miscellaneous Labs
- pH: 7.35–7.45; PaCO₂: 35-45; HCO₃: 22-26.
- Glucose: 70-115, fasting <100, HbA1c <6.5%.
- UA: specific gravity 1.003–1.030; high = concentrated/dehydrated; WBC, nitrites = infection.
Key Terms & Definitions
- BMP — Basic Metabolic Panel, a group of key blood tests.
- CBC — Complete Blood Count, tests WBC, RBC/Hgb/Hct, and platelets.
- INR/PTT — Coagulation test for blood thinning medication monitoring.
- Troponin — Protein marker for heart muscle injury.
- BUN/Creatinine — Waste markers for kidney function.
- Albumin — Liver-produced protein; low in liver failure.
- Ammonia — Protein waste elevated in liver dysfunction.
- Hypoglycemia — Low blood glucose, risk of brain death.
- Neutropenia — Low WBC, high infection risk.
Action Items / Next Steps
- Memorize all normal lab ranges and max "danger" values.
- Complete related study guides for BMP, CBC, and coagulation panels.
- Practice NCLEX-style questions focusing on safety interventions for abnormal labs.
- Review ABG interpretation methods and key causes of acid-base imbalances.