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Neuroscience of Learning and Memory
Aug 14, 2024
Learning and Brain Changes
Understanding Learning
Learning isn't just about studying; it involves changes in the brain.
Key Concept
: The brain doesn't grow new cells to store memories; instead, it strengthens connections between neurons.
Synaptic Plasticity
Definition
: The ability of synapses (the junctions between neurons) to change their strength.
Example: Long-term potentiation (LTP), which is a process that strengthens synaptic connections.
Neurons and Synaptic Communication
Neurons use electrochemical signals (electricity + chemicals) to communicate.
Two types of neurons at a synapse:
Pre-synaptic neuron
: Sends signals leading up to the synapse.
Post-synaptic neuron
: Receives the signal after the synapse.
Process of Synaptic Communication
Stimulation
: Pre-synaptic neuron releases neurotransmitters (chemical signals).
Binding
: Neurotransmitters bind to receptors on the post-synaptic neuron.
Ion Flow
: Channels open allowing ions (such as sodium and calcium) to flow into the post-synaptic neuron.
Potential Change
: The flow of ions changes the electrical charge difference (potential) across the neuron membrane.
Measuring Synapse Strength
Synapse strength is measured by the change in the post-synaptic neuron's potential due to pre-synaptic stimulation.
With repeated stimulation, synapses become more efficient, leading to greater post-synaptic potential.
Long-Term Potentiation (LTP)
Mechanism
: After repeated practice, the pre-synaptic neuron improves at sending signals to the post-synaptic neuron, increasing synapse strength.
Duration
: Strengthened synapses can last from minutes to months.
Significance
: LTP is believed to be the physiological basis for learning and memory retention.
Conclusion
Strengthened synapses allow for easier recall of experiences, highlighting the importance of synaptic plasticity in learning.
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