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Acne and Accutane: Side Effects, Treatment Considerations, and Patient Experiences
Jul 20, 2024
Lecture on Acne and Accutane by Dr. Joyce Park
Introduction
Dr. Joyce Park, board-certified dermatologist.
Focus on reacting to acne and Accutane related videos and sharing knowledge about Accutane.
What is Accutane?
Accutane
: Oral vitamin A used for treating severe nodulocystic acne.
Not for everyone due to various side effects.
Common Side Effects
Dry eyes, lips, and mucous membranes (nosebleeds).
Worsening of eczema, dry itchy skin.
Rare Side Effects
Mood changes (irritability, exacerbation of depression/anxiety).
Bone pain and hair loss.
Decrease in ovarian reserve and temporary impact on female fertility.
Teratogenic effects: risk of birth defects. Requires monthly pregnancy tests and strict birth control measures.
Headaches, decreased night vision, pyogenic granulomas, paronychia.
Blood test abnormalities: elevated triglycerides, altered liver function.
Considerations Before Prescribing Accutane
Type of acne: reserved for severe, recalcitrant, scarring, painful acne.
Moderate acne unresponsive to other treatments may qualify.
High risk of permanent scars.
Hormonal acne: influenced by androgens, may need ongoing treatment after Accutane.
Hormonal Acne Treatment
Various hormonal treatments like spironolactone or birth control.
Accutane may improve but not eliminate hormonal acne.
Dosage and Course of Treatment
Treatment length: typically 5-7 months, varies by severity and weight.
Goal dose determination via weight and clinical response.
Adjustments for side effects or lack of response.
Acne Fulminans
Explosive, painful acne exacerbation after starting Accutane.
Common in severe acne cases, treated by lowering Accutane dose and administering prednisone.
Video Reactions
Video 1: Daisy CBJ’s Transformation
Results
: Significant reduction in active breakouts and scarring after 6 months.
Discussion
: Importance of proper dosing and monitoring progression.
Note on Acne Fulminans
: Risk for severe cases, treated by dosage adjustment and prednisone.
Video 2: Compilation with Nosebleed
Explanation
: Nosebleeds due to drying effects of Accutane.
Remedies
: Use of humidifier, Vaseline for nose, and petrolatum for lips. Refresh tears for dry eyes.
Video 3: Multiple Courses of Accutane
Recurrence
: Up to one-third of patients may need multiple courses.
Vitamin A Absorption
: Take Accutane with fatty foods for better absorption.
Video 4: Accutane and Nose Shape
Debunking Claims
: Accutane does not alter nasal cartilage or shape; it only reduces pore size.
Conclusion
Overview of Accutane’s effects, indications, and video reactions.
Encouragement to leave questions and feedback for future content.
Additional Points
Importance of following prescribed guidelines during treatment.
Regular follow-ups and blood tests to monitor side effects.
Consultation with healthcare providers for personalized treatment strategies.
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Full transcript