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Abdominal Epilepsy Overview

Jun 21, 2025

Overview

This lecture covers abdominal epilepsy, a rare and often misdiagnosed neurological cause of abdominal pain, emphasizing its symptoms, diagnostic challenges, and treatment methods.

What is Abdominal Epilepsy?

  • Abdominal epilepsy is a rare form of temporal lobe epilepsy presenting as repeated episodes of abdominal pain, nausea, and vomiting.
  • It primarily affects children and can be accompanied by loss of consciousness or postictal sleepiness.
  • Due to overlapping symptoms with common abdominal disorders, it is frequently misdiagnosed as psychogenic pain.

Symptoms of Abdominal Epilepsy

  • Episodes last 5–20 minutes and occur unpredictably, unlike abdominal migraines which last hours to days.
  • Pain is usually centered around the belly button but may affect other abdominal regions.
  • Episodes may include migraine-like symptoms (headache, nausea, vomiting), and sometimes loss of consciousness or generalized seizures.
  • Patients may experience a postictal state with lethargy and increased sleepiness after episodes.
  • Abdominal pain may serve as an aura, warning of an impending larger seizure.

Diagnostic Challenges and Misdiagnosis

  • Physicians often focus on gastrointestinal causes and perform abdominal imaging and lab tests first.
  • After ruling out physical causes, patients are sometimes referred to psychiatry and labeled with psychogenic pain or conversion disorder.
  • Misdiagnosis is common, especially in children and in those from lower socioeconomic backgrounds.
  • This stigma and misdiagnosis delay effective treatment and may discourage further medical help.

Diagnosing and Treating Abdominal Epilepsy

  • An electroencephalogram (EEG) can detect epileptiform brain activity and help confirm the diagnosis.
  • Diagnosis is supported if antiepileptic drugs like Trileptal or Valproic reduce or eliminate symptoms.
  • Effective management is possible with correct diagnosis and anticonvulsant medication.
  • Gastrointestinal causes should be ruled out before considering neurological evaluation for abdominal pain.

Key Terms & Definitions

  • Abdominal Epilepsy — Rare epilepsy with episodes of abdominal pain and neurological symptoms.
  • Temporal Lobe Epilepsy — Seizures originating in the temporal lobe of the brain.
  • Aura — A warning sign or feeling before a seizure occurs.
  • Postictal State — Period of lethargy or confusion after a seizure.
  • EEG (Electroencephalogram) — A test recording the brain's electrical activity to detect seizures.
  • Psychogenic Pain — Physical pain originating from psychological rather than physical causes.
  • Conversion Disorder — A psychiatric condition where neurological symptoms appear without a physical cause.

Action Items / Next Steps

  • Review abdominal epilepsy symptoms and contrast with abdominal migraine.
  • Understand the importance of EEG in diagnosing neurological causes of abdominal pain.
  • Read about antiepileptic drugs and their use in treatment.