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Understanding Hyperkalemia: Causes and Management

Apr 16, 2025

Hyperkalemia Lecture Notes

Introduction

  • Presenter: Sarah from Register Nurse RN
  • Topic: Hyperkalemia (high potassium in the blood)
  • Related topic: Hypokalemia (covered in a previous video)
  • Recommended resources: RegisterNurseRN.com for quizzes and additional resources.

Understanding Hyperkalemia

  • Definition: Excessively high potassium levels in the blood.
  • Normal Potassium Levels: 3.5 to 5.1 mEq/L (varies slightly by source).
  • Dangerous Levels: Levels above 7 mEq/L require fast intervention.

Cellular Level Explanation

  • Potassium is primarily intracellular.
  • Blood tests measure extracellular potassium.
  • Hyperkalemia: Excess potassium moves from cells into blood.

Function of Potassium

  • Responsible for nerve conduction and muscle contraction.
  • Excess potassium disrupts these functions.

Causes of Hyperkalemia

  • C.A.R.E.D mnemonic:
    • C: Cellular movement from intracellular to extracellular (e.g., burns, tissue damage, acidosis).
    • A: Adrenal insufficiency (e.g., Addison's disease).
    • R: Renal failure (common in dialysis patients).
    • E: Excessive intake (supplements, diet).
    • D: Drugs (potassium-sparing diuretics, ACE inhibitors, NSAIDs).

Signs and Symptoms

  • M.U.R.D.E.R mnemonic:
    • M: Muscle weakness.
    • U: Urine output reduction (especially in renal failure).
    • R: Respiratory failure (due to muscle and nerve dysfunction).
    • D: Decreased cardiac contractility (weak pulse, low BP).
    • E: Early signs - muscle twitching/cramps; late signs - profound weakness.
    • R: Rhythm changes (tall T-waves, flat P-waves, wide QRS complexes, prolonged PR interval).

EKG Changes

  • Normal EKG:
    • P wave, QRS complex, T wave.
  • Hyperkalemia EKG:
    • Flat P waves, prolonged PR interval, wide QRS, tall T-waves.

Interventions

  • Monitoring: Cardiac, respiratory, neurological, muscular, and GI status.
  • Treatment Actions:
    • Stop IV potassium and hold supplements.
    • Start potassium-restricted diet.
    • Prepare for dialysis if required.
    • Use Kayexalate (sodium polystyrene sulfonate) to promote potassium excretion.
    • Administer potassium-wasting diuretics (e.g., Lasix).
    • Use hypertonic glucose and insulin to shift potassium back into cells.

Dietary Considerations

  • Potassium-rich Foods: Potatoes, pork, oranges, tomatoes, avocados, strawberries, spinach, fish, mushrooms, muskmelon, carrots, raisins, bananas.
  • Important for hypokalemia management (encourage) and hyperkalemia (restrict).

Conclusion

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