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Understanding Creatine Supplement Benefits

Apr 25, 2025

Lecture Notes: The Benefits of Creatine Supplementation

Introduction

  • Creatine is a top supplement, not just for bodybuilders but a game-changer for everyone.
  • Episode to cover five evidence-based reasons to include creatine in a daily routine.
  • New studies will be discussed, including creatine's cognitive benefits after poor sleep.

What is Creatine?

  • Creatine is a non-protein amino acid, mainly produced in the liver, also in the pancreas and kidneys.
  • Key role in cellular metabolism and energy production, especially in high-energy demand organs (muscle, brain, heart, bone tissues).
  • About 95% of the body's creatine is in muscle cells.
  • Allows cells to produce more ATP (energy currency).
  • Synthesized from amino acids: arginine, glycine, methionine.
  • Discovered in meat by French scientist in 1832.

Reasons to Supplement with Creatine

1. Improves Strength, Muscle Mass, and Body Composition

  • Meta-analyses show creatine monohydrate improves strength, muscle mass, and body composition.
  • Increases time to exhaustion, allowing greater work before fatigue.
  • Benefits amplified when combined with resistance training.
  • Men generally respond more favorably due to baseline creatine levels.
  • Dosage: 3-5g/day or 0.1g/kg.

2. Enhances Recovery and Performance for Endurance Athletes

  • Beneficial for prolonged endurance exercise involving high-intensity surges.
  • Enhances glycogen storage and replenishment, aiding energy availability.
  • Experimentation needed to balance weight gain with endurance performance.

3. May Help Improve Osteoarthritis

  • Study on postmenopausal women showed improved physical function and quality of life with creatine and resistance training.
  • Especially beneficial for non-severe osteoarthritis cases.

4. Brain Recovery After Stress

  • Creatine helps cognitive performance post sleep deprivation.
  • Study showed improved memory, reaction speed, and reduced fatigue.
  • High doses required for brain bioavailability.

5. May Improve Bone Health

  • Creatine may alter bone geometry, potentially reducing fracture risk.
  • Research suggests supplementing with resistance training may enhance bone strength.

Types of Creatine

  • Creatine monohydrate is the most studied and recommended form.
  • Alternative forms (ethyl ester, HCL, buffered) lack evidence of superior benefits.
  • Choose products with verified sources like CreaPure and NSF certification.

Dosage Recommendations

  • General use: 3-5g/day or 0.1g/kg for muscle and strength benefits.
  • Cognition (post sleep deprivation): 35g/kg.
  • Bone health: 0.14g/kg.

Safety and Practicality

  • Safe for most individuals, except those with kidney disease.
  • Concerns about hair loss unsubstantiated.
  • Food sources cannot adequately provide high creatine levels; supplementation is practical.

Conclusion

  • Creatine is a versatile supplement with multiple health benefits.
  • Recommended brand: Momentous Creatine Monohydrate.
  • Encourage sharing the knowledge and subscribing for updates.