Summary of Anxiety and Depression Medications

Feb 12, 2025

Medications for Anxiety and Depression

Introduction

  • Presenter: Cathy from Level Up RN
  • Topics: Medications for anxiety and depression, including SSRIs and SSNRIs
  • Includes a quiz at the end

Selective Serotonin Reuptake Inhibitors (SSRIs)

  • Common Medications: Paroxetine, Sertraline, Fluoxetine
  • Uses: Treat anxiety, depression, OCD, PTSD
  • Mechanism: Inhibit reuptake of serotonin, increasing its levels in the brain
  • Key Interactions:
    • St. John's Wort increases serotonin levels, risking serotonin syndrome
  • Serotonin Syndrome Symptoms:
    • Agitation, fever, muscle rigidity, tachycardia, nausea, vomiting, diaphoresis
  • Common Side Effects:
    • Sexual dysfunction, weight gain, insomnia
  • Onset: Full effects may take several weeks

Selective Serotonin and Norepinephrine Reuptake Inhibitors (SSNRIs)

  • Common Medications: Duloxetine, Venlafaxine
  • Uses: Treat anxiety, depression, neuropathic pain
  • Mechanism: Inhibit reuptake of serotonin and norepinephrine
  • Key Interactions:
    • St. John's Wort increases serotonin syndrome risk when combined
  • Common Side Effects:
    • Fatigue, insomnia, GI upset (nausea, constipation), decreased libido
  • Cool Chicken Hint: "I don't need a deluxe apartment to be happy. I just need to take duloxetine for my depression."

Quiz Questions

  1. Question: Patients can expect to feel the full effects of an SSRI within three to five days. True or False?

    • Answer: False. It can take several weeks.
  2. Question: Taking St. John's Wort with an SSRI or SSNRI increases the risk of what serious complication?

    • Answer: Serotonin syndrome
  3. Question: Sexual dysfunction is a common side effect of SSRIs and SSNRIs. True or False?

    • Answer: True

Conclusion

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