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Fats and Fatty Acids Overview

Jul 18, 2025

Overview

This lecture covers the structure, types, digestion, health impacts, and dietary recommendations of fats and fatty acids in nutrition.

Structure and Types of Fats

  • Fats are composed of glycerol (3-carbon backbone) and fatty acid chains.
  • Fatty acids are chains of carbon and hydrogen; classified by chain length: short (2–5C), medium (6–12C), and long (13+C).
  • The process linking glycerol and fatty acids releases water and forms mono-, di-, or triglycerides.
  • Saturated fatty acids have only single carbon bonds, are straight, and usually solid at room temperature.
  • Unsaturated fatty acids have one or more double bonds, causing kinks and are usually liquid at room temperature.
  • Monounsaturated fatty acids have one double bond; polyunsaturated have two or more.

Classification by Double Bond Position

  • The “omega” system numbers carbons from the methyl end to the first double bond (omega-3, omega-6, omega-9).
  • Omega-3 fats include ALA (from plants), EPA, and DHA (from fish/marine sources).
  • Omega-6 includes linoleic acid (plant oils) and arachidonic acid (animal sources).
  • Omega-9 (oleic acid) is found in canola/olive oil, almonds, and can be made by the body.

Cis and Trans Fats

  • Most natural unsaturated fats are in a cis configuration, causing bends and fluidity.
  • Trans fats have straight chains due to the trans configuration, leading to solidity.
  • Trans fats are produced by partial hydrogenation of oils and are associated with health risks.

Digestion and Absorption

  • Triglycerides are hydrophobic and form fat globules.
  • Lipases and bile salts help break fats into monoglycerides and free fatty acids.
  • These form micelles, which enter intestinal cells, reform as triglycerides, and are packaged into chylomicrons.
  • Chylomicrons enter the lymphatic system, then the blood, delivering fats to tissues.

Health Impacts & Recommendations

  • Polyunsaturated fats are precursors to prostaglandins, help lower blood pressure, and improve cholesterol profiles.
  • Long-chain omega-3 fatty acids lower plasma triglycerides and support infant brain and eye development.
  • The effects of saturated fats vary; replacement with polyunsaturated fats is beneficial, but not so with refined carbs.
  • Recommended fat intake is 20–35% of daily calories, with less than 10% from saturated fat and minimal trans fat.

Key Terms & Definitions

  • Triglyceride — Fat molecule with three fatty acids linked to glycerol.
  • Saturated Fat — Fatty acid with no double bonds, solid at room temperature.
  • Unsaturated Fat — Fatty acid with one or more double bonds, liquid at room temperature.
  • Monounsaturated Fatty Acid — Fatty acid with one double bond.
  • Polyunsaturated Fatty Acid — Fatty acid with two or more double bonds.
  • Cis/Trans Configuration — Arrangement of atoms around a double bond; cis causes bends, trans is straighter.
  • Chylomicron — Lipoprotein particle that transports dietary fats from the intestine to the bloodstream.

Action Items / Next Steps

  • Review recommended dietary fat intake and types of fats in your own diet.
  • Read more about the health effects of different fatty acids, especially omega-3 and omega-6 sources.