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Medication Routes Overview

Jun 17, 2025

Overview

This lecture covers the main routes of medication administration, their advantages, disadvantages, and considerations for selecting the best method for patients.

Oral (Per Os/PO) Route

  • Oral administration involves swallowing pills or liquids.
  • Advantages: safe, convenient, easy to store, cost-effective, with options for immediate or extended release.
  • Disadvantages: not suitable for children, elderly, unconscious, ventilated, or those with digestive issues.
  • Oral medications generally have slower absorption and distribution.

Sublingual and Buccal Routes

  • Sublingual administration: tablet placed under the tongue, absorbed directly into the bloodstream.
  • Buccal administration: tablet or lozenge placed between gum and cheek, absorbed through mucous membranes.
  • Both routes bypass the digestive system for quicker absorption and relief.

Transdermal Route

  • Medication applied through the skin, typically via a patch.
  • Delivers drugs directly to the bloodstream, with some patches controlling the delivery rate.
  • Useful for maintaining consistent medication levels over time.

Inhalation and Nasal Routes

  • Inhalation: breathing medication into the lungs through the mouth; provides rapid relief, especially for lung conditions like asthma.
  • Nasal administration: medication inhaled through the nose for local or systemic effects, useful for symptoms like nasal congestion.

Choosing a Route

  • Selection depends on medication type, desired absorption speed, patient condition, and convenience.
  • Healthcare provider consultation is advised for choosing the best administration route.

Key Terms & Definitions

  • Oral (PO, Per Os) — medication taken by mouth and swallowed.
  • Sublingual — medication placed under the tongue for direct absorption.
  • Buccal — medication placed between gum and cheek for absorption.
  • Transdermal — medication delivered through the skin via a patch.
  • Inhalation — medication breathed into the lungs.
  • Nasal Administration — medication inhaled through the nose.

Action Items / Next Steps

  • Review patient cases to determine appropriate medication routes.
  • Consult healthcare providers for route selection recommendations.