Overview
This lecture covers the types, components, and functions of connective tissue, emphasizing their structure, classification, and unique properties.
Types and Functions of Connective Tissue
- The four main types of connective tissue are connective tissue proper, cartilage, bone, and blood.
- Connective tissue functions include binding, support, protection, insulation, storage, and transportation.
- All connective tissues originate from embryonic mesenchyme.
Structure of Connective Tissue
- Connective tissue is composed of cells and an extensive extracellular matrix.
- The extracellular matrix consists of ground substance and fibers.
- Ground substance includes interstitial fluid, cell adhesion proteins, and proteoglycans.
- Fibers in connective tissue include collagen (strongest), elastic (stretchy), and reticular (supportive networks).
Cells of Connective Tissue
- Immature cells end with "-blast" and create matrix; mature cells end with "-cyte."
- Fibroblasts/fibrocytes form connective tissue proper; chondroblasts/chondrocytes form cartilage; osteoblasts/osteocytes form bone.
- Adipocytes (fat cells) and other cells are also present.
Connective Tissue Proper
- Subdivided into loose (areolar, adipose, reticular) and dense (regular, irregular, elastic) connective tissue.
- Areolar tissue is abundant, supportive, and stores fluid.
- Adipose tissue stores fat and insulates.
- Reticular tissue supports certain structures with a network of fibers.
- Dense regular tissue forms tendons and ligaments, resisting tension in one direction.
- Dense irregular tissue resists tension in multiple directions.
- Dense elastic tissue is primarily elastic fibers for stretch.
Cartilage
- Cartilage is tough, withstanding tension and compression, but lacks nerves and blood vessels.
- Hyaline cartilage is abundant, firm, and cushions structures.
- Elastic cartilage contains more elastic fibers and is flexible (e.g., ear).
- Fibrocartilage has rows of chondrocytes and collagen, found in intervertebral discs.
Bone and Blood
- Bone (osseous tissue) is hard due to collagen and inorganic calcium salts and contains blood vessels.
- Blood is a connective tissue with cells in a fluid matrix (plasma), originating from mesenchyme.
Key Terms & Definitions
- Mesenchyme — embryonic tissue from which all connective tissues derive.
- Extracellular matrix — non-cellular material (ground substance + fibers) surrounding connective tissue cells.
- Collagen fibers — strong, rope-like fibers providing tensile strength.
- Elastic fibers — stretchy fibers allowing tissue flexibility.
- Reticular fibers — thin, network-forming fibers supporting soft tissues.
- -blast — suffix indicating immature, matrix-producing cells (e.g., fibroblast).
- -cyte — suffix for mature, less active cells (e.g., osteocyte).
Action Items / Next Steps
- Review and compare structural features of each connective tissue type.
- Prepare for detailed study of blood, muscle tissue, and nervous tissue in future lessons.