Notes on Trenbolone: The Monster Steroid

Introduction

• Trenbolone referred to as the "monster steroid".
• Growing use beyond bodybuilders; recreational use noted.
• Extremely powerful with potentially devastating effects.

Scientific Background

• Member of the Nandrolone group, distinct from Nandrolone itself.
• Classification as a NOR-19 drug.
• Types of Trenbolone:
  • Trenbolone Acetate (FiniJect, Finiplex)
    • Initially for veterinary use, popular for intramuscular injection.
    • Used to increase muscle mass and appetite in cattle.
    • Concerns about drug presence in meat, with potential for trace contamination.
  • Trenbolone Hexahydrobenzylcarbonate (Parabolin, Hexabolin)
    • Briefly available in France for cachexia and severe muscle wasting, discontinued in 1997.
  • Trenbolone Enanthate
    • Not marketed for human or veterinary use; slow-acting, gained popularity in black market by 2004.

Side Effects

Estrogenic Effects

• Non-aromatizing steroid: no conversion to estrogen.
• High affinity for progesterone receptors leading to lactation in men.
• Gynecomastia not blocked by traditional anti-estrogen treatments; interactions with other steroids complicate effects.

Androgenic Effects

• 300% stronger than testosterone; causes hair loss, acne, and male pattern balding.
• Significant sexual side effects:
  • Hypersexuality in users.
  • Can lead to long-term hypogonadism post-use, affecting recovery of sexual function.

Cardiovascular Effects

• Adverse effects on lipid panel: decreased HDL, increased LDL.
• Can lead to left ventricular hypertrophy (LVH).
• Risk of prostate issues due to androgenic effects.

Behavioral Effects

• Aggressive behavior (roid rage) more pronounced with Trenbolone compared to other steroids.
• Users report increased irritability and potential for violence.

Renal Effects

• Increased risk of renal damage; linking to Focal Segmental Glomerulosclerosis (FSGS).
• Significant numbers of affected individuals requiring dialysis.

Trenbolone Cough

• Characterized by severe coughing following injection.
• Two hypotheses:
  • Increased prostaglandins affecting smooth muscle in the lungs.
  • Presence of bradykinin, leading to immediate cough reflex.

Conclusion

• Strong caution against use of Trenbolone.
• Users should consult healthcare professionals for guidance.
• Presentation by Dr. Thomas O'Connor; thank you for watching.