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Comprehensive Guide to Blood Transfusions

Apr 13, 2025

Blood Transfusions Overview

Introduction

  • Blood transfusion is a process where a patient low on red blood cells receives new red blood cells via venous access.
  • Commonly used to replenish red blood cells from blood donations when a patient is low due to:
    • Blood loss from surgery or trauma.
    • Severe anemia due to conditions like renal failure or cancer.

Importance of Red Blood Cells

  • Red blood cells, with hemoglobin, carry oxygen from the lungs throughout the body and remove carbon dioxide.
  • Symptoms of low red blood cells include:
    • Pallor (paleness).
    • Fatigue.
    • Shortness of breath.
    • Tachycardia (increased heart rate).

When to Transfuse

  • Depends on the patient’s condition and tolerance of low blood levels.
  • The American Association of Blood Banks recommends transfusions when hemoglobin levels fall to 7-8 grams per deciliter.
  • Normal hemoglobin levels:
    • Males: 14-18 grams per deciliter.
    • Females: 12-16 grams per deciliter.

Nurse's Role in Blood Transfusion

  • Preparation: Critical to prevent transfusion reactions.
    • Follow hospital protocols meticulously.
    • Type and cross-match the patient’s blood.
    • Ensure correct patient identification and documentation.
  • Informed Consent:
    • Explain procedure, assess understanding, and inquire about past transfusions and reactions.
    • Pre-medication may be required for patients with a history of reactions.
  • Check Patient Compatibility:
    • Know patient’s blood type and Rh factors.
    • Universal donor: O
    • Universal recipient: AB

Transfusion Process

  • IV Access:
    • Requires an 18-gauge or larger IV.
  • Supplies Needed:
    • Y tubing with an inline filter.
    • 0.9% Normal saline (the only solution compatible with blood transfusions).
  • Timing:
    • Transfuse one unit at a time within 4 hours to prevent bacterial growth.
  • Blood Warmers:
    • Use only if necessary for rapid transfusions to prevent hypothermia.
  • Verification with Another Nurse:
    • Check order, patient ID, blood type, expiration date, and the condition of blood.
  • Baseline and Continuous Monitoring:
    • Get baseline vitals, especially temperature.
    • Monitor signs of adverse reactions.

Transfusion Reactions

  • Types of Reactions:
    • Hemolytic Reaction: Immune system attacks donor red blood cells.
    • Allergic Reaction: Reaction to proteins in donor blood.
    • Febrile Reaction: Non-hemolytic, often due to prior transfusions.
    • GVHD: Graft-versus-host disease.
    • Circulatory Overload and Septicemia.

Common Signs of a Reaction (mnemonic: REACTION)

  • R: Rash
  • E: Elevated temperature
  • A: Ache (backache, chest pain)
  • C: Chills
  • T: Tachycardia
  • I: Increased respirations
  • O: Oliguria
  • N: Nausea

Response to a Transfusion Reaction

  • Immediate Actions:
    • Stop the transfusion.
    • Maintain IV access with saline.
    • Notify physician and blood bank.
  • Monitor Patient:
    • Stay at bedside, monitor vitals every 5 minutes.
    • Document the event thoroughly.

Conclusion

  • Ensure thorough preparation and monitoring during blood transfusions to ensure patient safety and minimize risks of reactions.
  • Continual vigilance and adherence to protocols are vital for successful blood transfusion management.